Introduction to Functional Magnetic Resonance Imaging
Principles and Techniques

This second edition is an invaluable guide to fMRI, from introducing the basic ideas and principles to the underlying physics and physiology.

Richard B. Buxton (Author)

9780521899956, Cambridge University Press

Hardback, published 27 August 2009

470 pages, 54 b/w illus. 8 colour illus.
24 x 16.4 x 2.6 cm, 0.92 kg

'In this extensive book on the subject by Richard B. Buxton, a physicist by background and a leading authority on fMRI, you - the student, resident, or fellow in neuroimaging, or even the clinician, researcher or experienced neuroscientist - can study, understand a lot of neurological processes … The information in the chapters of this book is presented with a lot of visuals to facilitate your understanding of the various complex topics.' Biz India

Functional Magnetic Resonance Imaging (fMRI) has become a standard tool for mapping the working brain's activation patterns, both in health and in disease. It is an interdisciplinary field and crosses the borders of neuroscience, psychology, psychiatry, radiology, mathematics, physics and engineering. Developments in techniques, procedures and our understanding of this field are expanding rapidly. In this second edition of Introduction to Functional Magnetic Resonance Imaging, Richard Buxton – a leading authority on fMRI – provides an invaluable guide to how fMRI works, from introducing the basic ideas and principles to the underlying physics and physiology. He covers the relationship between fMRI and other imaging techniques and includes a guide to the statistical analysis of fMRI data. This book will be useful both to the experienced radiographer, and the clinician or researcher with no previous knowledge of the technology.

Part I. An Overview of Functional Magnetic Resonance Imaging
Section 1. Introduction to the Physiological Basis of Functional Neuroimaging: 1. Neural activity and energy metabolism
2. Cerebral blood flow and brain activation
Section 2. Introduction to Functional Magnetic Resonance Imaging: 3. Nuclear magnetic resonance
4. Magnetic resonance imaging
5. Imaging functional activity
Part II. Principles of Magnetic Resonance Imaging
Section 1. The Nature of the Magnetic Resonance Signal: 6. Basic physics of magnetism and NMR
7. Relaxation and contrast in MRI
8. Diffusion and the MR signal
Section 2. Magnetic Resonance Imaging: 9. Mapping the MR signal
10. MRI techniques
11. Noise and artifacts in MR images
Part III. Principles of Functional Magnetic Resonance Imaging
Section 1. Perfusion Imaging: 12. Contrast agent techniques
13. Arterial spin labeling techniques
Section 2. Blood Oxygenation Level Dependent Imaging: 14. The blood oxygenation level dependent effect
15. Design and analysis of BOLD experiments
16. Interpreting the BOLD response
Appendix. The physics of NMR.

Subject Areas: Neurosciences [PSAN], Medical imaging [MMP], Neurology & clinical neurophysiology [MJN]