Intratumor Diversity and Clonal Evolution in Cancer

This specialized volume of Advances in Cancer research is dedicated to the complex and largely unexplored field of intratumor diversity, with respect to differences in both genotype and phenotype among cell populations within tumors

David Gisselsson (Edited by)

9780123876881, Elsevier Science

Hardback, published 2 November 2011

368 pages
22.9 x 15.1 x 2.5 cm, 0.82 kg

This specialized volume of Advances in Cancer Research is dedicated to the complex and largely unexplored field of intratumor diversity, with respect to differences in both genotype and phenotype among cell populations within tumors.

1. Introduction
2. Role of telomere dysfunction in genetic intratumour diversity
3. How mitotic errors contribute to karyotypic diversity in cancer
4. Nuclear Remodelling as a Mechanism for Genomic Instability in Cancer
5. Cytogenetic Analysis of Tumor Clonality
6. Genotyping techniques to address diversity in tumors
7. Prostate Cancer as a Model System for Genetic Diversity in Tumours
8. Evolutionary mechanisms and diversity in cancer
9. Cancer stem cells in tumor heterogeneity
10. Cancer: Beyond Speciation

Subject Areas: Cellular biology [cytology PSF], Oncology [MJCL]