Freshly Printed - allow 10 days lead
Couldn't load pickup availability
In Vivo Models to Study Angiogenesis
Presents an overview of the most common assays used to study angiogenesis in vivo, helping researchers select the most appropriate technique
Domenico Ribatti (Author)
9780128140208, Elsevier Science
Paperback, published 21 August 2017
112 pages
22.9 x 15.1 x 0.9 cm, 0.22 kg
In Vivo Models to Study Angiogenesis provides the latest information and an overview of the most common assays for studying angiogenesis in vivo. Under physiological conditions, angiogenesis is tightly controlled, whereas increased production of angiogenic stimuli and/or reduced production of angiogenic inhibitors leads to abnormal neovascularization, such as occurs in cancer, chronic inflammatory disease, diabetic retinopathy, macular degeneration and cardiovascular disorders. Several genetic and epigenetic mechanisms are involved in the early development of the vascular system. This book presents the latest information from the extensive literature and research available. Evidence is now emerging that blood vessels themselves have the ability to provide instructive regulatory signals to surrounding non-vascular target cells during organ development. Thus, endothelial cell signaling is currently believed to promote fundamental cues for cell fate specification, embryo patterning, organ differentiation and postnatal tissue remodeling.
The chorioallantoic membrane
The corneal micropocket assay
The zebrafish embryo
The sponge implant method
The Matrigen implant assay
In vivo gene transfer with AAV vectors
In vivo tumor models
Subject Areas: Developmental biology [PSC], Biochemistry [PSB], Life sciences: general issues [PSA], Biophysics [PHVN]
