Immunotherapeutic Strategies for the Treatment of Glioma

A summary of recent and upcoming immunotherapeutic approaches for brain tumors

Christopher Jackson (Edited by), Michael Lim (Edited by)

9780128197554, Elsevier Science

Hardback, published 14 September 2021

190 pages
23.5 x 19 x 1.9 cm, 0.45 kg

Immunotherapeutic Strategies for the Treatment of Glioma provides a review of the current state of immunotherapy for primary brain tumors. The topic is of interest to patients, clinicians, and researchers alike, particularly given the recent failure of large clinical trials. This book serves as an overview of the most promising approaches in the field and provides a foundation for considering novel and combination therapies moving forward.
The book discusses several types of immunotherapies for glioma, such as peptide, dendritic cell and heat shock protein vaccines; immune checkpoint blockade; myeloid cells as target; oncolytic viruses; and CAR T cell therapy. Additionally, it discusses the mechanisms of immune suppression in patients and immunogenomics.
This volume is a valuable source for cancer researchers, oncologists and several members of biomedical field who are interested in novel strategies to fight glioblastoma.

1. Peptide vaccines 2. Dendritic cell vaccines 3. Heat shock protein vaccines 4. Immune checkpoint blockade 5. Targeting myeloid cells in glioblastoma 6. Oncolytic viruses 7. CAR T cell therapy 8. Mechanisms of immune suppression in glioblastoma patients 9. Immunogenomics in glioblastoma

Subject Areas: Life sciences: general issues [PSA]