Immunopotentiators in Modern Vaccines

Provides completely updated insights into the mechanism of action of modern immunopotentiators and their potential use in future vaccines

Virgil Schijns (Edited by), Derek O'Hagan (Edited by)

9780128040195

Hardback, published 10 November 2016

508 pages
23.4 x 19 x 3 cm, 1.22 kg

Approx.490 pages

1. Vaccine Adjuvants' Mode of Action: Unraveling ‘‘the Immunologist's Dirty Little Secret? 2. The Role of Inflammasomes in Adjuvant-Driven Humoral and Cellular Immune Responses 3. Dendritic Cells as Targets of Vaccines and Adjuvants 4. Host-Derived Cytokines and Chemokines as Vaccine Adjuvants 5. Discovery of Immune Potentiators as Vaccine Adjuvants 6. Current Status of Toll-Like Receptor 4 Ligand Vaccine Adjuvants 7. Flagellins as Adjuvants of Vaccines 8. Toll-Like Receptor 7 and 8 Agonists for Vaccine Adjuvant Use 9. CpG Oligodeoxynucleotides as Adjuvants for Clinical Use 10. Advax Adjuvant: A Potent and Safe Immunopotentiator Composed of Delta Inulin 11. Natural Vaccine Adjuvants and Immunopotentiators Derived From Plants, Fungi, Marine Organisms, and Insects 12. Polymeric Particles as Vaccine Delivery Systems 13. MF59: A Safe and Potent Adjuvant for Human Use 14. The Development of the Adjuvant System AS01: A Combination of Two Immunostimulants MPL and QS-21 in Liposomes 15. Development and Evaluation of AS04, a Novel and Improved Adjuvant System Containing 3-O-Desacyl-4'- Monophosphoryl Lipid A and Aluminum Salt 16. ISCOMATRIX Adjuvant in the Development of Prophylactic and Therapeutic Vaccines 17. Development and Evaluation of CAF01 18. Mineral Adjuvants 19. Toxin-Based Mucosal Adjuvants 20. Adjuvants for Skin Vaccination 21. Vaccination to Treat Noninfectious Diseases: Surveying the Opportunities 22. A Framework for Evaluating Nonclinical Safety of Novel Adjuvants and Adjuvanted Preventive Vaccines

Subject Areas: Immunology [MJCM], Public health & preventive medicine [MBN]