Immunology
Volume 1: Immunotoxicology, Immunopathology, and Immunotherapy

Covers the very broad subject of immunomodulation and the role of autophagy and immunotherapy in (auto)immune diseases and health

M. A. Hayat (Edited by)

9780128098196, Elsevier Science

Paperback, published 27 October 2017

286 pages
23.4 x 19 x 1.9 cm, 0.54 kg

Immunology, Volume 1: Immunotoxicology, Immunopathology, and Immunotherapy discusses the investment of time, effort and finance that go into making progress in preventing and/or curing serious diseases by using standard treatments (chemotherapy, radiotherapy, surgery, and hormone therapy). The use of these treatments is accompanied by unavoidable, devastating side effects. At the cost of being repetitious, it has to be emphasized that an improved understanding of the immune system, avoidance of unhealthy habits (e.g., smoking, intake of alcohol, perpetual stress, and lack of exercise) and early detection (using biomarkers) are the only three friends we have to at least delay the onset of serious diseases.

I. MOLECULAR MECHANISMS 1. Introduction to Immunology  2. Cytomegalovirus and Autophagy 3. The Role of Macroautophagy in T Cells 4. Increased Immunogenicity through Autophagy 5. Regulation of Humoral Immunity by CD1D-Restricted Natural Killer T Cells 6. Signaling by the Toll-like Receptors Induces Autophagy through Modification of Beclin-1: Molecular Mechanism 7. Molecular Mechanisms Underlying the Action of Ipilimumab against metastatic melanoma 8. To Help or To Harm: Dynamic Roles of CD4+ T Helper Cells in Solid Tumor Microenvironments 9. Development and Function of Nk Cells and its Importance in Cancer Immunotherapy

Subject Areas: Medical microbiology & virology [MMFM], Immunology [MJCM]