• Immunologic Concepts in Transfusion Medicine (Paperback / softback) 9780323675093
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Immunologic Concepts in Transfusion Medicine

A comprehensive resource on the immune aspects of blood component transfusion

Robert W Maitta (Edited by)

9780323675093, Elsevier Health Sciences

Paperback / softback, published 27 August 2019

380 pages
23.4 x 19 x 2.4 cm, 0.77 kg

Immunological Concepts in Transfusion Medicine provides a thorough discussion of the immune aspects of blood component transfusion, with in-depth information on the intricacies of immune responses to blood components and the immune processes that may be initiated in response to blood exposure. Written to increase knowledge and awareness of immune challenges such as alloimmunization and transfusion-related acute lung injury, this title bridges current basic scientific discoveries and the potential effects seen in blood recipients.

  • Complies the knowledge and expertise of Dr. Robert Maitta, an expert in immune responses and antibody function/structure studies.

  • Helps clinicians in the daily practice of caring for patients in need of transfusion support, as well as physicians in training when considering utilizing blood transfusions in a limited scope or in the setting of massive transfusion.

  • Includes an immunology primer as an introduction to in-depth chapters covering allergic immune reactions to blood components, transfusion-related immunomodulation, fetal and neonatal alloimmune thrombocytopenia and neonatal neuthropenia, complications of haploidentical and mismatched HSC transplantation, chimeric antibody receptor therapies, and much more.
  • Consolidates today’s available information on this timely topic into a single, convenient resource.

1 Immunology primer
2 Mechanisms of alloimmunization to RBC antigens and testing methodologies
3 Autoimmunity: cold and warm autoantibodies, and autoimmune hemolytic anemia
4 Allergic immune reactions to blood components
5 Changing landscape in transfusion-transmitted infections
6 Transfusion-related immunomodulation
7 Transfusion-related acute lung injury
8 HLA-alloimmunization, platelet refractoriness, and post-transfusion purpura
9 Alloimmunization in pregnancy
10 Fetal and neonatal alloimmune thrombocytopenia, and neonatal neutropenia
11 Alloimmunization in chronically-transfused patients and those with malignancies
12 Graft-versus-Host disease and Transfusion-associated Graft-versus-Host disease
13 Complications of ABO- and non-ABO-incompatible stem cell transplantations
14 Complications of haploidentical and mismatched HSC transplantation
15 Apheresis therapy in immunological disorders and its immune complications
16 Passive monoclonal and polyclonal antibody therapies
17 Chimeric antigen receptor therapies

Subject Areas: Medicine [M]
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