Hyaluronan Signaling and Turnover

Advances in Cancer Research provides invaluable information on the exciting and fast-moving field of cancer research. Here, once again, outstanding and original reviews are presented on a variety of topics.

Melanie Simpson (Author), Paraskevi Heldin (Author)

9780128000922

Hardback, published 30 July 2014

418 pages
22.9 x 15.1 x 2.7 cm, 0.84 kg

Approx.380 pages

1.Emerging Roles for Hyaluronidase in Cancer Metastasis and Therapy2.Targeting Hyaluronic Acid Family for Cancer Chemoprevention & Therapy3.Aberrant Post-Transcriptional Processing of Hyaluronan Synthase 1 in Malignant Transformation and Tumor Progression 4.Hyaluronan Synthases Post-Translational Regulation in Cancer5.Hyaluronon-Coated Extracellular Vesicles – A Novel Link Between Hyaluronan and Cancer6.Hyaluronan in the Healthy and Malignant Hematopoietic Microenvironment7.Hyaluronan Regulation of Endothelial Barrier Function in Cancer8.HAS2 and CD44 in Breast Tumorigenesis9.CD44 is a Multidomain Signaling Platform that Integrates Extracellular Matrix Cues with Growth Factor and Cytokine Signals10.Hyaluronan-CD44 Interaction Promotes Oncogenic Signaling, MicroRNA Functions, Chemoresistance and Radiation Resistance in Cancer Stem Cells Leading to Tumor Progression11.Advances and Advantages of Nanomedicine in the Pharmacological Targeting of Hyaluronan-CD44 Interactions and Signaling in Cancer12.Hyaluronan / RHAMM Interactions in Mesenchymal Tumor Pathogenesis: Role of Growth Factors13.CD147: Regulator of Hyaluronan Signaling in Invasiveness and Chemoresistance

Subject Areas: Molecular biology [PSD], Oncology [MJCL]