Human Germline Genome Modification and the Right to Science
A Comparative Study of National Laws and Policies

A survey of the regulation of human germline genome modification in eighteen countries and the emerging international standards.

Andrea Boggio (Edited by), Cesare P. R. Romano (Edited by), Jessica Almqvist (Edited by)

9781108499873, Cambridge University Press

Hardback, published 9 January 2020

324 pages, 6 b/w illus. 8 tables
23.5 x 15.6 x 4 cm, 1.07 kg

The advent of the CRISPR/Cas9 class of genome editing tools is transforming not just science and medicine, but also law. When the genome of germline cells is modified, the modifications could be inherited, with far-reaching effects in time and scale. Legal systems are struggling with keeping up with the CRISPR revolution and both lawyers and scientists are often confused about existing regulations. This book contains an analysis of the national regulatory framework in eighteen selected countries. Written by national legal experts, it includes all major players in bioengineering, plus an analysis of the emerging international standards and a discussion of how international human rights standards should inform national and international regulatory frameworks. The authors propose a set of principles for the regulation of germline engineering, based on international human rights law, that can be the foundation for regulating heritable gene editing both at the level of countries as well as globally.

1. Introduction Andrea Boggio,Cesare P. R. Romano and Jessica Almqvist
2. The governance of human (germline) genome modification at the international and transnational level
Part I. North America: 3. The regulation of human germline genome modification in Canada Erika Kleiderman
4. The regulation of human germline genome modification in the United States Kerry Lynn Macintosh
5. The regulation of human germline genome modification in Mexico María de Jesús Medina Arellano
Part II. Europe: 6. The regulation of human germline genome modification in Europe Jessica Almqvist and Cesare P. R. Romano
7. The regulation of human germline genome modification in the United Kingdom James Lawford Davies
8. The regulation of human germline genome modification in Germany Timo Faltus
9. The regulation of human germline genome modification in Belgium Guido Pennings
10. The regulation of human germline genome modification in Sweden Santa Slokenberga and Heidi Carmen Howard
11. The regulation of human germline genome modification in the Netherlands Britta van Beers, Charlotte de Kluiver and Rick Maas
12. The regulation of human germline genome modification in Italy Ludovica Poli
13. The regulation of human germline genome modification in Spain Iñigo de Miguel Beriain and Carlos María Romeo Casabona
14. The regulation of human germline genome modification in France Alessandro Blasimme, Dorothée Caminiti and Effy Vayena
15. The regulation of human germline genome modification in Switzerland Alessandro Blasimme, Dorothée Caminiti and Effy Vayena
Part III. Asia: 16. The regulation of human germline genome modification in Japan Tetsuya Ishii
17. The regulation of human germline genome modification in The People's Republic of China Lingqiao Song and Rosario Isasi
18. The regulation of human germline genome modification in The Republic of Korea Hannah Kim and Yann Joly
19. The regulation of human germline genome modification in Singapore Calvin W. L. Ho
Part IV. Other OECD Countries: 20. The regulation of human germline genome modification in Australia Dianne Nicol
21. The regulation of human germline genome modification in Israel Vardit Ravitsky and Gali Ben-Or
22. Towards a human rights framework for the regulation of human germline genome modification Andrea Boggio, Cesare P. R. Romano and Jessica Almqvist.

Subject Areas: Medical & healthcare law [LNTM], Comparative law [LAM], Law [L]