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How to Scale-Up a Wet Granulation End Point Scientifically

An essential resource on the scale-up of wet granulation end points for pharmaceutical scientists and technologists engaged in granulation processes.

Michael Levin (Author)

9780128035221, Elsevier Science

Paperback, published 22 October 2015

88 pages
22.9 x 15.1 x 0.8 cm, 0.16 kg

How to Scale-Up a Wet Granulation End Point Scientifically provides a single-source devoted to all relevant information on the scale-up of a wet granulation end point.

Contents include a general description, problem identification, and theoretical background with supporting literature, case studies, potential solutions, and more. By outlining issues related to scale-up and end-point determination, and then using practical examples and advice to address these issues, How to Scale-Up a Wet Granulation End Point Scientifically is a valuable and essential resource for all those pharmaceutical scientists and technologists engaged in the granulation process.

1. Scale-Up Basics2. Dimensional Analysis, Principle of Similitude, Dimensionless Numbers, Comparison of attainable Froude Numbers3. Scientific scale-up procedure4. Case Studies5. Practical Considerations for End-Point Scale-Up6. List of Symbols and Dimensions, Literature Reference

Subject Areas: Organic chemistry [PNN], Pharmacology [MMG]

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