Handbook of Pharmaceutical Wet Granulation
Theory and Practice in a Quality by Design Paradigm

Sets a benchmark in the contemporary knowledge and understanding of the pharmaceutical wet granulation process

Ajit S Narang (Edited by), Sherif Badawy (Edited by)

9780128104606

Hardback, published 4 December 2018

890 pages, 40 illustrations (40 in full color)
23.4 x 19 x 4.3 cm, 2.04 kg

Handbook of Pharmaceutical Wet Granulation: Theory and Practice in a Quality by Design Paradigm offers a single and comprehensive reference dedicated to all aspects of pharmaceutical wet granulation, taking a holistic approach by combining introductory principles with practical solutions. Chapters are written by international experts across industry, academic and regulatory settings, and cover a wide spectrum of relevant and contemporary wet granulation topics, techniques and processes. The books' focus on process analytical technology, quality by design principles, granulation equipment, modeling, scale-up, control and real time release makes it a timely and valuable resource for all those involved in pharmaceutical wet granulation.

Section I: Physicochemical Principles and Fundamentals of Wet Granulation Section II: Critical Quality Attributes of Drug Products and Process Design Solutions Section III:  Process-Stability Interactions and Optimization Section IV:  Material Attributes Critical to Wet Granulation Process Performance Section V: Process Modeling Section VI: Scale-up Section VII:  Process Development and Process Analytical Technology Applications Section VIII:  Real-Time Release, Real-time Release Testing, and Drug Product Control Strategy Development

Subject Areas: Biochemistry [PSB], Pharmacology [MMG]