Handbook of Neural Activity Measurement

Underlying principles of the various techniques are explained, enabling neuroscientists to extract meaningful information from their measurements.

Romain Brette (Edited by), Alain Destexhe (Edited by)

9780521516228, Cambridge University Press

Hardback, published 6 September 2012

489 pages, 95 b/w illus. 30 colour illus.
25.5 x 18 x 2.7 cm, 1.17 kg

"The book is an important reference for neuroscientists who use these techniques in their own experimental protocols and need to interpret heir results precisely; for computational neuroscientists who use such experimental results in their models; and for scientists who want to develop new measurement techniques or enhance existing ones." -Mathematical Reviews

Neuroscientists employ many different techniques to observe the activity of the brain, from single-channel recording to functional imaging (fMRI). Many practical books explain how to use these techniques, but in order to extract meaningful information from the results it is necessary to understand the physical and mathematical principles underlying each measurement. This book covers an exhaustive range of techniques, with each chapter focusing on one in particular. Each author, a leading expert, explains exactly which quantity is being measured, the underlying principles at work, and most importantly the precise relationship between the signals measured and neural activity. The book is an important reference for neuroscientists who use these techniques in their own experimental protocols and need to interpret their results precisely, for computational neuroscientists who use such experimental results in their models, and for scientists who want to develop new measurement techniques or enhance existing ones.

Preface
1. Introduction Romain Brette and Alain Destexhe
2. Electrodes Thomas Stieglitz
3. Intracellular recording Romain Brette and Alain Destexhe
4. Extracellular spikes and CSD Klas H. Pettersen, Henrik Lindén, Anders M. Dale and Gaute T. Einevoll
5. Local field potentials Claude Bédard and Alain Destexhe
6. EEG and MEG – forward modelling J. C. de Munck, C. H. Wolters and M. Clerc
7. EEG and MEG – source estimation Seppo P. Ahlfors and Matti S. Hämäläinen
8. Intrinsic signal optical imaging Ron D. Frostig and Cynthia H. Chen-Bee
9. Voltage-sensitive dye imaging S. Chemla and F. Chavane
10. Calcium imaging Fritjof Helmchen
11. Functional Magnetic Resonance Imaging Andreas Bartels, Jozien Goense and Nikos Logothetis
12. Perspectives Romain Brette and Alain Destexhe.

Subject Areas: Neurosciences [PSAN], Mensuration & systems of measurement [PDDM], Mathematical modelling [PBWH]