Handbook of Experimental Neurology
Methods and Techniques in Animal Research

An essential 2006 reference volume covering major methodologies and disease models in current neuroscience research.

Turgut Tatlisumak (Edited by), Marc Fisher (Edited by)

9780521184205, Cambridge University Press

Paperback, published 23 December 2010

594 pages
24.4 x 17 x 3.1 cm, 0.93 kg

Basic relevant information on methodologies used in neurological disease models can be extremely hard to find. Originally published in 2006, this important reference work contains 30 chapters from over 60 internationally recognized scientists and covers every major methodology and disease model used in neuroscience research. Divided into two major sections, the first deals with general methodologies in neuroscience research covering topics from animal welfare and ethical issues to surgical procedures, post-operative care and behavioral testing. Section two covers every major disease model including traumatic brain injury, ischemia and stroke, to Parkinson's, motor neurone disease, epilepsy and sleep disorders. Delivering critical methodological information and describing small animal models for almost all major neurological diseases, this book forms an essential reference for anyone working in neuroscience, from beginning students to experienced researchers and medical professionals.

Preface
Part I. Principles and General Methods: 1. Introduction: Animal modelling - a precious tool for developing remedies to neurological diseases Turgut Tatlisumak and Marc Fisher
2. Ethical issues, welfare laws, and regulations David Whittaker
3. Housing, feeding, and maintenance of rodents Robert W. Kemp
4. Identification of individual animals Turgut Tatlisumak and Daniel Strbian
5. Analgesia, anesthesia, and postoperative care in laboratory animals Naoya Masutomi and Makoto Shibutani
6. Euthanasia in small animals Turgut Tatlisumak
7. Various surgical procedures in rodents René Remie
8. Genetically engineered animals Carolina M. Maier, Lilly Hsieh and Pak H. Chan
9. Imaging in experimental neurology Marc Fisher, Eng H. Lo and Michael Lev
10. Safety in animal facilities Tarja Kohila
11. Behavioural testing in small animal models: ischemic stroke Larry B. Goldstein
12. Methods for analysing brain tissue Päivi Liesi
13. Targeting molecular constructs of cellular function and injury through in vitro and in vivo experimental models Zhao Zhong Chong, Faqi Li and Kenneth Maiese
14. Neuroimmunology and immune-related neuropathologies Bao-Guo Xiao and Hans Link
15. Animal models of sex differences in non-reproductive brain functions George T. Taylor, Juergen Weiss and Frank Zimmermann
16. The ependymal route for central nervous system gene therapy Erica Butti, Gianvito Martino and Roberto Furlan
17. Neural transplantation Stephen B Dunnett, Eduardo M. Torres, Monte A. Gates, and Rosemary A. Fricker-Gates
Part II. Experimental Models of Major Neurological Diseases: 18. Focal brain ischemia models in rodents Fuhai Li and Turgut Tatlisumak
19. Rodent models of global brain ischemia Julia Kofler and Richard J. Traystman
20. Rodent models of hemorrhagic stroke Fatima A. Sehba and Joshua B. Bederson
21. In-vivo models of traumatic brain injury Ronen R Leker and Shlomi Constantini
22. Experimental models for the study of CNS tumors Taichang Jang and Lawrence Recht
23. Experimental models for demyelinating diseases Jason M Link, Richard E. Jones, Halina Offner and Arthur A Vandenbark
24. Animal models of Parkinson's disease Anumantha G. Kathasamy and Siddharth Kaul
25. Animal models of epilepsy Ricardo M. Arida, Alexandre V. Silva, Margareth R. Priel, and Esper A. Cavalheiro
26. Experimental models of hydrocephalus Osaama H. Khan and Marc R. Del Bigio
27. Rodent models of experimental bacterial infections in the CNS Tammy Kielian
28. Experimental models of motor neuron disease Ruth Danzeisen, Birgit Schwalenstöcker and Albert C Ludolph
29. Animal models for sleep disorders Seiji Nishino and Nobuhiro Fujiki
30. Experimental models of muscle diseases Anu Suomalainen, Katja E. Peltola, Anders Paetau and Carina Wallgren-Pettersson.

Subject Areas: Neurosciences [PSAN], Neurology & clinical neurophysiology [MJN]