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Genomics and Precision Healthcare
Innovations, Applications and Challenges
Swetha Kumari Koduru (Edited by), Sarad Pawar Naik Bukke (Edited by), Hussaini Bello (Edited by), Muhamad Mustafa Mundu (Edited by), Ayush Madan (Edited by)
9781394367528, Wiley
Hardback, published 3 June 2026
528 pages
22.9 x 15.2 x 3.2 cm, 0.851 kg
Unlock the future of individualized patient care with this guide to mastering the interdisciplinary synergy of next-generation sequencing, clinical diagnostics, and ethical frameworks that define the new era of precision medicine. The field of genomics has witnessed remarkable growth over the past few decades, fundamentally altering the landscape of healthcare and medical research. The rapid advancement of genomic technologies, particularly next-generation sequencing and the growing understanding of the human genome, has opened new frontiers in diagnostics, treatment, and prevention. Genomics now sits at the intersection of molecular biology, bioinformatics, pharmacology, and clinical medicine, forming the foundation of precision healthcare. This book explores the transformative impact of genomics on modern medicine, from foundational principles of genetics to cutting-edge clinical applications. It examines how genomic technologies are reshaping diagnosis and treatment across conditions such as cancer, rare diseases, and infectious diseases, while highlighting the rise of precision medicine—an approach that tailors therapies based on individual genetic profiles. The book also addresses key challenges in integrating genomic data into healthcare systems, including ethical considerations in genetic testing, genomic counseling, and evolving healthcare policy. With a global perspective, it provides insights into the opportunities and complexities of implementing genomic medicine across diverse healthcare environments.
Preface xxiii 1 The Fundamentals of Genetics and Genomics: A Primer for Healthcare Professionals 1 2 From Gene Discovery to Clinical Applications: The Journey of Genomic Research 39 3 Precision Medicine: Tailoring Treatments to Genetic Profiles 67 4 Genomic Technologies in Diagnostic Medicine: Advances and Applications 97 5 Pharmacogenomics: How Genetic Information Influences Drug Response 139 6 Ethical, Legal, and Social Implications of Genomic Data in Healthcare 171 7 The Role of Genomics in Rare and Noncommunicable Diseases 201 8 Cancer Genomics: Innovations in Diagnosis, Prognosis and Therapy 233 9 Genomic Research in Infectious Diseases: Impact and Advances 255 10 Genomics of Prenatal and Paediatric Diseases: Early Detection and Intervention 295 11 Integrating Genomic Data into Electronic Health Records (EHRs) 351 12 Genomic Counseling: Navigating the Complexities of Genetic Risk and Inheritance 373 13 Healthcare Policy and Genomics: Shaping the Future of Health Care Systems 419 14 Patient Perspectives and Experiences with Genomic Testing 441 15 Global Prospectives on Genomic Healthcare: Opportunities and Challenges 463 Acknowledgment 485 Index 489
K. Haripriya, Swetha Kumari Koduru and K. Nandini
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Ashok Thulluru, Goutham Yerrakula, Nawaz Mohammed, Reshma Tadipatri and Varun Srighakollapu
Pradeep Natarajan
G. Avinash Kumar, P. Pravallika, V. Thirumalai, Chandrashekar Thalluri and Sarad Pawar Naik Bukke
M. Reddy Sailaja, Swetha Kumari Koduru and R. Venkata Raghava Reddy
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References 485
Subject Areas: Biology, life sciences [PS]
