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Genomic and Precision Medicine
Foundations, Translation, and Implementation
Reviewing the implementation of genomic medicine across public health systems and throughout society while discussing the fundamental aspects of infrastructure, policy, and research, this book pinpoints the challenges, barriers, and solutions that enable translation of genome based technologies into health care
Geoffrey S. Ginsburg (Edited by), Huntington F Willard (Edited by)
9780128006818, Elsevier Science
Hardback, published 20 December 2016
398 pages
22.9 x 15.1 x 2.6 cm, 0.77 kg
"...I believe there is nothing similar on the market. This book is unique as a well-done and clearly presented compilation of information. It is easy to read and captures the inquisitive minds of readers. Further editions will be well received. Score: 98 - 5 Stars" --Doody's
Genomic and Precision Medicine: Foundations, Translation, and Implementation highlights the various points along the continuum from health to disease where genomic information is impacting clinical decision-making and leading to more personalization of health care. The book pinpoints the challenges, barriers, and solutions that have been, or are being, brought forward to enable translation of genome based technologies into health care. A variety of infrastructure (data systems and EMRs), policy (regulatory, reimbursement, privacy), and research (comparative effectiveness research, learning health system approaches) strategies are also discussed. Readers will find this volume to be an invaluable resource for the translational genomics and implementation science that is required to fully realize personalized health care.
1. Application of Human Genome Information to Clinical Practice
2. Translating genome information into clinical practice and human health
3. Big Data and Translational Bioinformatics Genomic and Personalized Medicine
4. Designing Genome-Based Clinical Studies
5. Developing the Evidence to Support Clinical Use Genomic Biomarkers as Diagnostics
6. Health Risk Assessment and Family History
7. Clinical Decision Support
8. Implementation Science and Integration into Healthcare Systems
9. Pharmacogenetics and Pharmacogenomics
10. Drug Repurposing and Repositioning
11. Point of Care Devices
12. Overview of Policy, Ethical and Social Considerations
13. Educational Issues and Strategies for Genomic Medicine
14. Regulation of Genomic Technologies
15. Economic Value of Genomic Medicine
16. Reimbursement
17. Impact of Patents on Genomic Medicine
Subject Areas: Pharmacology [MMG], Diseases & disorders [MJC], Medical genetics [MFN]
