Genomic and Precision Medicine
Cardiovascular Disease

Reviews the critical genetic underpinnings of cardiovascular disease, synthesizing basic biology with systems biology approaches

Geoffrey S. Ginsburg (Edited by), Huntington F Willard (Edited by)

9780128018125, Elsevier Science

Hardback, published 10 November 2017

336 pages, 60 illustrations
22.9 x 15.1 x 2.4 cm, 0.7 kg

Genomic and Precision Medicine: Cardiovascular Disease, Third Edition, focuses on the applications of genome discovery on the broad spectrum of cardiovascular disorders. Each chapter is organized for the application of genomics and personalized medicine tools and technologies to a) Risk Assessment and Susceptibility, b) Diagnosis and Prognosis, c) Pharmacogenomics and Precision Therapeutics, and d) Emerging and Future Opportunities in the field.

1. Overview: A Systems Approach To Cardiovascular Medicine
2. Application of Human Genome Information to Clinical Practice
3. Translating genome information into clinical practice and human health
4. Big Data and Translational Bioinformatics Genomic and Personalized Medicine
5. Health Risk Assessment and Family History
6. Clinical Decision Support
7. Overview of Policy, Ethical and Social Considerations
8. Hypertension
9. Lipoprotein Disorders
10. Coronary Artery Disease and Myocardial Infarction
11. The Vulnerable Plaque and Acute Coronary Syndromes
12. Heart Failure
13. Hypertrophic Cardiomyopathies
14. Arrhythmias
15. Hemostasis and Thrombosis
16. Peripheral Arterial Disease
17. Congenital Heart Disease
18. Perioperative Genomics
19. Stroke
20. Novel Approaches to Cardiovascular Diagnostics
21. Cardiovascular Pharmacogenomics
22. Case Studies

Subject Areas: Pharmacology [MMG], Medical genetics [MFN]