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Genome Plasticity in Health and Disease

Provides a thorough overview of genome plasticity in humans, emphasizing its role in physiology, disease and adaptation

Diego A. Forero (Volume editor), George P. Patrinos (Volume editor)

9780128178195

Paperback, published 7 April 2020

288 pages, 100 illustrations (30 in full color)
23.4 x 19 x 1.9 cm, 0.6 kg

Approx.274 pages

1. Impact of Genome Plasticity on Health and Disease

Section I. Plasticity of the Human Genome 2. Overview of the Human Genome 3. Methods for Epigenomic Analyses: DNA Methylation 4. Genomic Databases 5. Genomic Variability: Germline, Somatic and de novo Variants 6. Founder Variations in Isolated Populations 7. DNA Methylation 8. Chromatin, Histones and Histone Modifications in Health and Diseases 9. Networks of Transcription Factors 10. Centromere and Telomere Dynamics in Humans

Section II. Human Genome Plasticity and Diseases 11. Genome Plasticity and Cardiovascular Diseases 12. Genome Plasticity and Neuropsychiatric Disorders 13. Genome Plasticity and Endocrine Diseases 14. Implications of Genome Plasticity for Drug Development

Subject Areas: Molecular biology [PSD], DNA & Genome [PSAK1], Genetics [non-medical PSAK]

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