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Gene Therapy for Viral Infections
Offers considerations for employing gene therapy and synthetic nucleic acids to achieve antiviral effects
Patrick Arbuthnot (Author)
9780124105188, Elsevier Science
Hardback, published 24 June 2015
392 pages
23.4 x 19 x 2.6 cm, 1.04 kg
Gene Therapy for Viral Infections provides a comprehensive review of the broader field of nucleic acid and its use in treating viral infections. The text bridges the gap between basic science and important clinical applications of the technology, providing a systematic, integrated review of the advances in nucleic acid-based antiviral drugs and the potential advantages of new technologies over current treatment options. Coverage begins with the fundamentals, exploring varying topics, including harnessing RNAi to silence viral gene expression, antiviral gene editing, viral gene therapy vectors, and non-viral vectors. Subsequent sections include detailed coverage of the developing use of gene therapy for the treatment of specific infections, the principles of rational design of antivirals, and the hurdles that currently face the further advancement of gene therapy technology.
1. Essentials of Gene Therapy for Viral infections2. Harnessing RNAi to silence Viral Gene Expression3. Antiviral sequence-specific DNA binding proteins4. Viral Gene Therapy Vectors5. Nonviral vectors6. Gene therapy for HBV infection7. Gene therapy for HCV infection8. Gene therapy for HIV infection 9. Gene therapy for respiratory and other viral infections10. Gene therapy for hemorrhagic fever viruses11. Gene transfer for vaccination against viral infection12. Conclusion
Subject Areas: Virology [non-medical PSGL], Genetics [non-medical PSAK], Medical genetics [MFN]
