Gene-Environment Interactions in Birth Defects and Developmental Disorders

This volume explores new approaches to resolve complex gene-environment interactions as a challenging but navigable path toward birth defect prevention

Robert J. Lipinski (Volume editor), Robert S. Krauss (Volume editor)

9780128201572, Elsevier Science

Hardback, published 27 January 2023

296 pages
22.9 x 15.1 x 2.3 cm, 0.45 kg

Gene-Environment Interactions in Birth Defects and Developmental Disorders, Volume 152, covers the multifactorial etiology of a variety of developmental disorders, including orofacial clefts, fetal alcohol spectrum disorders, autism, and others. The causes of individual cases of most common birth defects are unknown but likely involve a combination of genetic predisposition and environmental exposures. How these risk factors interact in the genesis of these conditions is still largely unknown and readers will find the latest information and ideas on these disorders, along with discussion of the challenges and opportunities for furthering knowledge in this area.

1. Gene-environment interactions in birth defect etiology: Challenges and opportunities
   Robert J. Lipinski and Robert S. Krauss
2. Transgenerational inheritance and its modulation by environmental cues
   Roxane Verdikt, Abigail A. Armstrong, and Patrick Allard
3. Gene-alcohol interactions in birth defects
   Joshua L. Everson and Johann K. Eberhart
4. The role of genes and environment in the etiology of congenital diaphragmatic hernias
   Nathan G. Burns and Gabrielle Kardon
5. Gene–environment interactions in the pathogenesis of common craniofacial anomalies
   Sharien Fitriasari and Paul A. Trainor
6. Gene×environment associations in orofacial clefting
   Mary L. Marazita
7. Gene–environment interactions underlying the etiology of neural tube defects
   Carlo Donato Caiaffa, Cristiane Sá Roriz Fonteles, Lei Yunping, and Richard H. Finnell
8. Gene×environment interactions in autism spectrum disorders
   Kimberly Keil-Stietz and Pamela J. Lein
   

Subject Areas: Botany & plant sciences [PST]