Gap Junction Structure and Chemical Regulation
Direct Calmodulin Role in Cell-to-Cell Channel Gating

Comprehensive analysis on the structure and chemical regulation of direct cell-to-cell communication via gap junction channels

Camillo Peracchia (Author)

9780128161500, Elsevier Science

Paperback, published 18 February 2019

226 pages
23.4 x 19 x 1.5 cm, 0.41 kg

Gap Junction Structure and Chemical Regulation: Direct Calmodulin Role in Cell-to-Cell Channel Gating describes and discusses the findings of major studies conducted during the past century on the structure and chemical regulation of direct cell-to-cell communication via gap junction channels. Chapters bring together important findings on direct cell communication, from its history, to its structure and regulation. These channels are essential for normal organ function, and mutations in their protein (connexin) cause various diseases. The book is useful for established investigators who need a review on the field and young investigators who need a thorough resource for study and comprehension.

1. Historical background2. Ultrastructure3. Molecular structure4. Chemical gating - I. Role of intracellular calcium and hydrogen ions5. Chemical gating - II. Direct calmodulin role6. Chemical gating - III. Models7. Connexin-related diseases8. Future perspectives9. Further reading

Subject Areas: Life sciences: general issues [PSA]