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Fundamentals of Toxicology
Essential Concepts and Applications
A concise, approachable overview of the basic concepts of toxicology, this foundational text covers commonly used definitions, historical perspectives, regulatory requirements, good laboratory practices, types of toxicology testing and evaluation, toxic agents and their adverse effects on health, and analytical, forensic, and diagnostic toxicology
P.K. Gupta (Author)
9780128054260
Paperback, published 25 August 2016
422 pages
23.4 x 19 x 2.7 cm, 0.81 kg
Fundamentals of Toxicology: Essential Concepts and Applications provides a crisp, easy-to-understand overview of the most important concepts, applications, and ideas needed to learn the basics of toxicology. Written by a pre-eminent toxicologist with over five decades of teaching experience, this comprehensive resource offers the hands-on knowledge needed for a strong foundation in the wide field of toxicology. Fundamentals of Toxicology includes a clear structure divided into five units to assist learning and understanding. The first unit provides extensive coverage on the background of toxicology including commonly used definitions and historical perspective, while following units cover: basic concepts; regulatory requirements and good laboratory practices, including types of toxicology testing and evaluation; toxic agents and adverse effects on health; and analytical, forensic, and diagnostic toxicology. This is an essential book for advanced students in toxicology and across the biomedical sciences, life sciences, and environmental sciences who want to learn the concepts of toxicology, as well as early researchers needing to refresh outside of their specialty.
Unit I Chapter 1. Introduction and historical background Chapter 2. Definitions and scope of toxicology Chapter 3. Classification of poisons/toxicants Chapter 4. Factors affecting toxicity Chapter 5. Natural laws concerning toxicology Chapter 6. Hazard and risk assessment Unit II Chapter 7. Absorption, distribution, and excretion of toxicants Chapter 8. Biotransformation Chapter 9. Principles and basic concepts of toxicokinetics Unit III Chapter 10. Toxicological testing: Genesis Chapter 11. Toxicological testing: In vitro models Chapter 12. Toxicological testing: In vivo systems Chapter 13. Genotoxicity Chapter 14. Preclinical toxicological investigations of pharmaceutical products Chapter 15. Preclinical safety evaluation of biotechnology-derived products Chapter 16. Preclinical regulatory toxicology for biomaterials and medical devices Unit IV Chapter 17. Toxic effects of pesticides (agrochemicals) Chapter 18. Toxic effects of metals Chapter 19. Toxic effects of nonmetallics Chapter 20. Neurotoxic agents Chapter 21. Toxic effects of cardiac poisons Chapter 22. Toxic effects of asphyxiants Chapter 23. Toxic effects of caustics (corrosives) Chapter 24. Drug toxicity, dependence, and abuse Chapter 25. Toxic effects of domestic chemicals Chapter 26. Toxic effects of poisonous plants Chapter 27. Poisonous foods and food poisoning Chapter 28. Poisons of animal origin Chapter 29. Chemical food poisoning Chapter 30. Health effects of radioactive materials Unit V Chapter 31. Basic concepts of forensic toxicology Chapter 32. Applications in toxicology Chapter 33. Clinical toxicology Chapter 34. Treatment of poisoning
Subject Areas: Medical toxicology [MMGT]
