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Functional Neuromarkers for Psychiatry
Applications for Diagnosis and Treatment
This cutting edge book explores, in detail, the brain pattern biomarkers for psychiatric and neurologic disorders and how they can be used in diagnosis, determining personalized neurotherapy, and monitoring treatment results. Focuses on the analysis of EEG and ERP, and covers the functional neuromarkers for ADHD, schizophrenia, and obsessive-compulsive disorder.
Juri D. Kropotov (Author)
9780124105133
Hardback, published 25 May 2016
498 pages
22.9 x 15.1 x 3 cm, 0.95 kg
Functional Neuromarkers for Psychiatry explores recent advances in neuroscience that have allowed scientists to discover functional neuromarkers of psychiatric disorders. These neuromarkers include brain activation patterns seen via fMRI, PET, qEEG, and ERPs. The book examines these neuromarkers in detail—what to look for, how to use them in clinical practice, and the promise they provide toward early detection, prevention, and personalized treatment of mental disorders. The neuromarkers identified in this book have a diagnostic sensitivity and specificity higher than 80%. They are reliable, reproducible, inexpensive to measure, noninvasive, and have been confirmed by at least two independent studies. The book focuses primarily on the analysis of EEG and ERPs. It elucidates the neuronal mechanisms that generate EEG spontaneous rhythms and explores the functional meaning of ERP components in cognitive tasks. The functional neuromarkers for ADHD, schizophrenia, and obsessive-compulsive disorder are reviewed in detail. The book highlights how to use these functional neuromarkers for diagnosis, personalized neurotherapy, and monitoring treatment results.
Introduction Part 1 - Methods of assessing neuromarkersChapter 1.1 - Theory of measurementChapter 1.2 - Psychometrics and neuropsychological assessmentChapter 1.3 - Functional MRIChapter 1.4 - Positron emission tomographyChapter 1.5 - Spontaneous electroencephalogramChapter 1.6 - Event-related potentials Part 2 - Neuromarkers of cortical self-regulationChapter 2.1 - Infraslow electrical oscillationsChapter 2.2 - Alpha rhythmsChapter 2.3 - Beta and gamma rhythmsChapter 2.4 - Frontal midline theta rhythm Part 3 - Information flow within the brainChapter 3.1 - Sensory systems and attention modulationChapter 3.2 - Executive system and cognitive controlChapter 3.3 - Affective system, emotions and stressChapter 3.4 - Memory systems Part 4 - Methods of neuro-modulationChapter 4.1 - Pharmacological approachChapter 4.2 - NeurofeedbackChapter 4.3 - Electroconvulsive therapyChapter 4.4 - Transcranial Direct Current StimulationChapter 4.5 - Transcranial magnetic stimulationChapter 4.6 - Deep Brain Stimulation Part 5 - Neuromarkers in psychiatryChapter 5.1 - Attention deficit hyperactivity disorderChapter 5.2 - SchizophreniaChapter 5.3 - Obsessive-compulsive disorder Part 6 - Assessing functional neuromarkersChapter 6.1 - Working hypothesisChapter 6.2 - Technical implementationChapter 6.3 - Testing working hypothesis: spontaneous EEGChapter 6.4 - Testing working hypothesis: Event-Related ProposalsChapter 6.5 - Monitoring treatment effects Part 7 - The State of the Art: Overview Chapter 7.1 - Objective Measures of Human Brain Functioning Chapter 7.2 - Rhythms of the Healthy Brain Chapter 7.3 - Information Flow in the Health Brain Chapter 7.4 - Current Treatment Options in Psychiatry Chapter 7.5 - Functional Neuromarkers in Diseased Brain Chapter 7.6 - Implementation in Clinical Practice
Subject Areas: Neurosciences [PSAN], Clinical psychology [MMJ]
