Formulation Tools for Pharmaceutical Development

J E Aguilar (Edited by)

9781907568992, Elsevier Science

Hardback, published 30 September 2013

304 pages
23.3 x 15.6 x 2.3 cm, 0.64 kg

"This is a handy reference. The authors' experiences with various tools in modeling and optimizing formulation are concisely presented. The book is expected be a useful resource for formulation scientists." --Doody's Book Review

A range of new and innovative tools used for preformulation and formulation of medicines help optimize pharmaceutical development projects. Such tools also assist with the performance evaluation of the pharmaceutical process, allowing any potential gaps to be identified. These tools can be applied in both basic research and industrial environment. Formulation tools for pharmaceutical development considers these key research and industrial tools.Nine chapters by leading contributors cover: Artificial neural networks technology to model, understand, and optimize drug formulations; ME_expert 2.0: a heuristic decision support system for microemulsions formulation development; Expert system for the development and formulation of push-pull osmotic pump tablets containing poorly water-soluble drugs; SeDeM Diagram: an expert system for preformulation, characterization and optimization of tables obtained by direct compression; New SeDeM-ODT expert system: an expert system for formulation of orodispersible tablets obtained by direct compression; and 3D-cellular automata in computer-aided design of pharmaceutical formulations: mathematical concept and F-CAD software.

Artificial neural networks technology to model, understand, and optimize drug formulations
ME_expert 2.0: A heuristic decision support system for microemulsions formulation development
Expert system for the development and formulation of push–pull osmotic pump tablets containing poorly water- soluble drugs
SeDeM Diagram: An expert system for preformulation, characterization and optimization of tablets obtained by direct compression
New SeDeM-ODT expert system: An expert system for formulation of orodispersible tablets obtained by direct compression
3-D cellular automata in computer-aided design of pharmaceutical formulations: Mathematical concept and F-CAD software
OXPIRT: Ontology- based eXpert system for Production of a generic Immediate Release Tablet
Optimisation of compression parameters with AI-based mathematical models.

Subject Areas: Pharmacology [MMG]