Formulation of Monoclonal Antibody Therapies
From Lab to Market

Comprehensive and accessible overview of recent advances of using mAbs with a focus on the formulation aspects

Amal Ali Elkordy (Author)

9780128233658, Elsevier Science

Paperback, published 23 May 2023

346 pages, 25 illustrations (5 in full color)
22.9 x 15.2 x 2.2 cm, 0.45 kg

Formulation of Monoclonal Antibody Therapies: From Lab to Market covers a wide range of topics about therapeutic monoclonal antibodies (mAbs) with a focus on formulation aspects. Therapeutic monoclonal antibodies are used for treatment of chronic diseases. It brings together a comprehensive knowledge in one accessible volume. Starting with foundational information on monoclonal antibodies, the book then discusses the importance of biopharmaceutical products, monoclonal antibodies, and biosimilars in treatment of chronic diseases, pharmaceutical aspects of mAbs, and how it can be administered. It also covers the industrial point of view and the clinical application of mAbs including in oncology, general medicine, rheumatology, hematology, dermatology, gastrointestinal tract, metabolic diseases, and dentistry. Formulation of Monoclonal Antibody Therapies: From Lab to Market is essential reading for researchers in biotechnology and biopharmaceutical fields, academics and pharmaceutical industrial scientists, and university students in pharmaceutical and biopharmaceutical sciences.

1. Introduction about monoclonal antibodies
2. Biosimilar antibodies
3. Pharmaceutical aspects of mAbs: formulation, characterization, and current route of administration of monoclonal antibody therapies
4. Route of monoclonal antibodies administration
5. Industrial aspects of finished monoclonal antibody therapies
6. Application of approved and marketed products of monoclonal antibody therapies

Subject Areas: Biotechnology [TCB], Pharmacology [MMG], Cytology [MFCC], Pharmaceutical industries [KNDP]