Fly Models of Human Diseases

Covers fly models of human diseases by presenting a comprehensive set of reviews from an international board of authors

Leslie Pick (Volume editor)

9780128029046

Hardback, published 5 January 2017

454 pages
22.9 x 15.1 x 2.8 cm, 0.91 kg

Approx.434 pages

1. Fly Models of Human Diseases: Drosophila as a Model for Understanding Human Mitochondrial Mutations and Disease Aditya Sen and Rachel T. Cox 2. Drosophila as a Model for Human Diseases - Focus on Innate Immunity in Barrier Epithelia Peter Bergman, Shiva Seyedoleslami Esfahani and Ylva Engström 3. Drosophila melanogaster as a Model of Muscle Degeneration Disorders Rebecca E. Kreipke, Young V. Kwon, Halyna R. Shcherbata and Hannele Ruohola-Baker 4. Amyotrophic Lateral Sclerosis Pathogenesis Converges on Defects in Protein Homeostasis Associated with TDP-43 Mislocalization and Proteasome-Mediated Degradation Overload Guang Lin, Dongxue Mao and Hugo J. Bellen 5. Mechanisms of Parkinson's Disease: Lessons from Drosophila Victoria L. Hewitt and Alexander J. Whitworth 6. Neurotoxicity Pathways in Drosophila Models of the Polyglutamine Disorders Megan Krench and J. Troy Littleton 7. AxGxE: Using Flies to Interrogate the Complex Etiology of Neurodegenerative Disease Christopher Burke, Kien Trinh, Vidya Nadar and Subhabrata Sanyal 8. Unraveling the Neurobiology of Sleep and Sleep Disorders Using Drosophila Leela Chakravarti, Emilia H. Moscato and Matthew S. Kayser 9. Modeling Human Cancers in Drosophila Masahiro Sonoshita and Ross L. Cagan 10. Stem-Cell-Based Tumorigenesis in Adult Drosophila Steven X. Hou and Shree Ram Singh 11. The Drosophila Accessory Gland as a Model for Prostate Cancer and Other Pathologies Clive Wilson, Aaron Leiblich, Deborah C. I. Goberdhan and Freddie Hamdy 12. Drosophila melanogaster Models of Galactosemia Jennifer M. I. Daenzer and Judith L Fridovich-Keil 13. Drosophila as a Model for Diabetes and Diseases of Insulin Resistance Patricia Graham and Leslie Pick

Subject Areas: Botany & plant sciences [PST], Developmental biology [PSC]