Freshly Printed - allow 7 days lead
Couldn't load pickup availability
Fluorescent Nanodiamonds
Huan-Cheng Chang (Author), Wesley Wei-Wen Hsiao (Author), Meng-Chih Su (Author)
9781119477082, Wiley
Hardback, published 16 November 2018
304 pages
24.6 x 17.5 x 2 cm, 0.726 kg
The most comprehensive reference on fluorescent nanodiamond physical and chemical properties and contemporary applications Fluorescent nanodiamonds (FNDs) have drawn a great deal of attention over the past several years, and their applications and development potential are proving to be manifold and vast. The first and only book of its kind, Fluorescent Nanodiamonds is a comprehensive guide to the basic science and technical information needed to fully understand the fundamentals of FNDs and their potential applications across an array of domains. In demonstrating the importance of FNDs in biological applications, the authors bring together all relevant chemistry, physics, materials science and biology. Nanodiamonds are produced by powerful cataclysmic events such as explosions, volcanic eruptions and meteorite impacts. They also can be created in the lab by high-pressure high-temperature treatment of graphite or detonating an explosive in a reactor vessel. A single imperfection can give a nanodiamond a specific, isolated color center which allows it to function as a single, trapped atom. Much smaller than the thickness of a human hair, a nanodiamond can have a huge surface area that allows it to bond with a variety of other materials. Because of their non-toxicity, nanodiamonds may be useful in biomedical applications, such as drug delivery and gene therapy. Fluorescent Nanodiamonds is an important working resource for a broad range of scientists and engineers in industry and academia. It will also be a welcome reference for instructors in chemistry, physics, materials science, biology and related fields.
Preface xi Acknowledgements xv Part I Basics 1 1 Introduction to Nanotechnology 3 1.1 Nanotechnology: From Large to Small 3 1.2 Nanocarbons: Now and Then 8 References 15 2 Nanodiamonds 19 2.1 Ah, Diamonds, Eternal Beautiful 19 2.2 Diamonds: From Structure to Classification 22 2.3 Diamond Synthesis 26 2.4 Nanodiamonds: A Scientist’s Best Friend 30 References 33 3 Color Centers in Diamond 37 3.1 Nitrogen Impurities 37 3.2 Crystal Defects 40 3.3 Vacancy]Related Color Centers 41 3.4 The NV− Center 47 References 50 4 Surface Chemistry of Nanodiamonds 55 4.1 Functionalization 56 4.2 Bioconjugation 61 4.3 Encapsulation 66 References 69 5 Biocompatibility of Nanodiamonds 73 5.1 Biocompatibility Testing 73 5.2 In Vitro Studies 77 5.3 Ex Vivo Studies 82 5.4 In Vivo Studies 83 References 86 Part II Specific Topics 91 6 Producing Fluorescent Nanodiamonds 93 6.1 Production 93 6.2 Characterization 101 References 110 7 Single Particle Detection and Tracking 113 7.1 Single Particle Detection 113 7.2 Single Particle Tracking 120 References 130 8 Cell Labeling and Fluorescence Imaging 135 8.1 Cell Labeling 135 8.2 Fluorescence Imaging 142 References 150 9 Cell Tracking and Deep Tissue Imaging 155 9.1 Cellular Uptake 155 9.2 Cell Tracking 161 9.3 Deep Tissue Imaging 165 References 171 10 Nanoscopic Imaging 175 10.1 Diffraction Barrier 176 10.2 Superresolution Fluorescence Imaging 177 10.3 Cathodoluminescence Imaging 184 10.4 Correlative Light]Electron Microscopy 188 References 191 11 Nanoscale Quantum Sensing 195 11.1 The Spin Hamiltonian 196 11.2 Temperature Sensing 197 11.3 Magnetic Sensing 207 References 211 12 Hybrid Fluorescent Nanodiamonds 215 12.1 Silica/Diamond Nanohybrids 215 12.2 Gold/Diamond Nanohybrids 217 12.3 Silver/Diamond Nanohybrids 226 12.4 Iron Oxide/Diamond Nanohybrids 228 References 232 13 Nanodiamond]Enabled Medicine 235 13.1 NDs as Therapeutic Carriers 236 13.2 Drug Delivery 237 13.3 Gene Therapy 244 13.4 Animal Experiments 247 References 249 14 Diamonds in the Sky 253 14.1 Unidentified Infrared Emission 253 14.2 Extended Red Emission 258 14.3 Cosmic Events at Home on Earth 264 References 267 Further Reading 271 Index 273
Subject Areas: Mechanical engineering & materials [TG]
