Essential Chemistry for Formulators of Semisolid and Liquid Dosages

This comprehensive book on chemistry for semisolid and liquid dosages explores stability testing methods such as particle size, rheological/viscosity, microscopy, and chemistry, and closes with a valuable discussion of regulatory issues. It offers scientists and students the foundation and practical guidance to make and analyze semisolid and liquid formulations

Vitthal S. Kulkarni (Author), Charles Shaw (Author)

9780128010242, Elsevier Science

Hardback, published 27 October 2015

256 pages
22.9 x 15.1 x 2.1 cm, 0.57 kg

A needed resource for pharmaceutical scientists and cosmetic chemists, Essential Chemistry for Formulators of Semisolid and Liquid Dosages provides insight into the basic chemistry of mixing different phases and test methods for the stability study of nonsolid formulations. The book covers foundational surface/colloid chemistry, which forms the necessary background for making emulsions, suspensions, solutions, and nano drug delivery systems, and the chemistry of mixing, which is critical for further formulation of drug delivery systems into semisolid (gels, creams, lotions, and ointments) or liquid final dosages. Expanding on these foundational principles, this useful guide explores stability testing methods, such as particle size, rheological/viscosity, microscopy, and chemical, and closes with a valuable discussion of regulatory issues. Essential Chemistry for Formulators of Semisolid and Liquid Dosages offers scientists and students the foundation and practical guidance to make and analyze semisolid and liquid formulations.

1. Introduction to the Chemistry of Mixing2. Surfactants, Lipids and Surface Chemistry3. Drug Delivery Vehicles4. Formulating Creams, Gels, Lotions and Suspensions5. Polymers and Thickeners in Semisolid Formulations6. Topical Aerosol and Nasal Sprays7. Formulation and Stability Testing8. Particle Size: An Overview of Various Methods9. Rheological/Viscosity Studies10. Microscopy Techniques (Optical and Electron Microscopy)11. Miscellaneous Physical, Chemical and Microbiological Test Methods12. An Overview of Regulatory Aspects for Pharmaceutical Semisolid Dosage

Subject Areas: Chemistry [PN], Pharmacology [MMG]