Enzyme Active Sites and their Reaction Mechanisms

Offers a detailed overview on the origin and function of enzymes, the chemical details of their active sites, mechanisms of action, and related co-factors

Harry Morrison (Author)

9780128210673, Elsevier Science

Paperback, published 4 December 2020

280 pages, 160 illustrations
22.9 x 15.1 x 1.9 cm, 0.45 kg

Enzyme Active Sites and their Reaction Mechanisms provides a one-stop reference on how enzymes "work." Here, Dr. Harry Morrison, PhD and Professor Emeritus at Purdue University, provides a detailed overview of the origin and function of forty enzymes, the chemical details of their active sites, their mechanisms of action, and associated cofactors. The enzymes featured highlight a step forward, along with possible areas of application, thus supporting new research in academic and industrial labs. Each chapter is written in a clear format, including a brief summary of enzyme function and structure, a detailed description of their mechanisms of action and associated co-factors.

1. Acetylcholinesterase2. Aconitase3. Adenosine deaminase4. Alcohol dehydrogenase5. Aldehyde dehydrogenase6. Arginase7. Carbonic anhydrase8. Carboxypeptidase A9. Chymotrypsin10. Citrate synthase11. Cytochrome P450cam12. m5C Cytosine methyltransferase13. Deoxyribodipyrimidine photolyase14. Dihydrolipoamide dehydrogenase15. Dihydrolipoyl transacetylase16. Farnesyl pyrophosphate synthase17. Fructose-1,6-bisphosphate aldolase18. Hepatitis C NS2/3 protease19. HIV-1 protease20. Indoleamine-Dioxygenase-121. Lysozyme22. Methyl-coenzyme M reductase23. Methylmalonyl CoenzymeA Mutase24. Non-heme iron halogenase25. Peptidylarginine deiminase26. Peptidylglycine a-hydroxylating monooxygenase27. Phenylalanine hydroxylase28. Phosphatidylinositol-specific phospholipase C29. Protein kinase A30. Pyruvate carboxylase31. Pyruvate dehydrogenase32. Ribonucleotide reductase33. Ribonuclease A34. Serine racemase35. Soluble quinoprotein glucose dehydrogenase36. Tetrachloroethene reductive dehalogenase37. Thymidylate synthase38. 20S Proteasome39. Uracil-DNA Glycosylase40. Vanadium-dependent chloroperoxidase

Subject Areas: Molecular biology [PSD], Enzymology [PSBZ], Biochemistry [PSB], Life sciences: general issues [PSA], Biophysics [PHVN]