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Endocrine Disruption and Human Health
Introductory reference describing endocrine disruptors and their effects on human health, risk and regulation
Philippa D. Darbre (Edited by)
9780128219850, Elsevier Science
Paperback, published 23 September 2021
538 pages, 100 illustrations (100 in full color)
23.5 x 19 x 3.3 cm, 1.09 kg
"Many books have been published about endocrine-disrupting chemicals. This updated second edition is a well-written, easy-to-read resource that is helpful for clinicians who want to learn more about the health implications of EDCs." --© Doody’s Review Service, 2021, Jessica Hwang, MD, reviewer, expert opinion
Updated with new and expanded chapters, Endocrine Disruption and Human Health, Second Edition provides an introduction to what endocrine disruptors are, the issues surrounding them, the source of these chemicals in the ecosystem and the mechanisms of action and assay systems. Contributions by specialists are included to discuss the varying effects of endocrine disruption on human health, and procedures for risk assessment of endocrine disruptors, and current approaches to their regulation are also covered. With new material on topics such as low-term, low dose mixtures, windows of susceptibility, epigenetics, EDCs effect on the gut microbiome, EDCs in from polluted air and oral exposures, green chemistry, and nanotechnology, the new edition of Endocrine Disruption and Human Health is a valuable and informative text for academic and clinical researchers and other health professionals approaching endocrine disruption and its effects on human health for the first time, graduate students, and advanced undergraduate students.
SECTION 1 OVERVIEW and SCOPE 1. What is endocrine disruption? 2. Which chemicals are endocrine disruptors? SECTION 2 MECHANISMS and ASSAY SYSTEMS 3. Environmental oestrogens: Disrupters of oestrogen action 4. Disrupters of androgen action 5. Assay systems for studying endocrine disruption 6. Non-monotonic responses in endocrine disruption 7. Endocrine disrupters as modifiers of endogenous hormone synthesis SECTION 3 CONCERNS FOR HUMAN HEALTH 8. Endocrine disruption and female reproductive health 9. Endocrine disruption and breast cancer 10. Endocrine disruption and male reproductive health 11. Endocrine disruption and prostate cancer 12. Endocrine disruption and thyroid disease 13. Endocrine disruption of adrenal function 14. Endocrine disruption of developmental pathways and children’s health 15. Endocrine disruption of immune function 16. Endocrine disruption and obesity, metabolic syndrome and type 2 diabetes 17. Endocrine disruption and cardiovascular disease 18. Transgenerational effects of endocrine disruption 19. Regulatory considerations
Subject Areas: Biomedical engineering [MQW]
