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Endocrine Biomarkers
Clinicians and Clinical Chemists in Partnership
A guide to currently known biomarkers associated with endocrinology and metabolism, their clinical applications, and laboratory methods used for detection
Hossein Sadrzadeh (Edited by), Gregory Kline (Edited by)
9780128034125, Elsevier Science
Hardback, published 27 September 2017
478 pages
23.4 x 19 x 2.9 cm, 1.18 kg
"There is a need for an endocrine text that combines clinical endocrinology with appropriate use of the laboratory since endocrine practice so heavily relies on laboratory testing.This need has been met by this excellent concise well written and easily understandable text book.The format is particularly appealing incorporating endocrine pathophysiology with appropriate and judicious use of laboratory testing and analysis. Intended for family physicians ,medical students,allied health practitioners and clinical chemists, it also provides a useful reference text for anyone interested in correctly assessing endocrine disease.Written by faculty primarily from the University of Calgary admirably led by Dr Hossein Sadrzadeh and Dr Gregory Kline. I endorse this book and look forward to continued updates as new hormone discoveries are made and new tests are developed. This book should allow us to adhere to the principle of ‘choosing wisely." --Robert G. Josse, BSc, MBBS, FRCP(UK), FRCPC, FACP, FACE, Division of Endocrinology and Metabolism, Associate Scientist, Li Ka Shing Knowledge Institute, Professor of Medicine and Nutritional Sciences, University of Toronto
Endocrine Biomarkers: Clinical Aspects and Laboratory Determination covers all the pre-analytical variables that can affect test results, both in the clinic and laboratory. Biomarkers of endocrine and bone diseases are discussed from both clinical and laboratory perspectives, and the authors elaborate on the teamwork-based app+roach between the clinician and the laboratory professional in the diagnosis and management of endocrine and bone disorders. Discussions include test utilization, laboratory measurement methods, harmonization and standardization, interpretation of results, and reference intervals. Each chapter ends with a discussion of one or two relevant cases with shared opinions from both a clinician and a clinical chemist. Each chapter also includes a summary box outlining key points and common pitfalls in the use of specific disease biomarkers and tests.
1. Preanalytical Variables 2. Thyroid 3. Diabetes, Metabolic Syndrome, and Cardiovascular Risk 4. Bone Metabolism 5. Adrenal Cortex and Hypertension 6. Parathyroid Glands, Calcitropic Hormones and Mineral Metabolism 7. Neuroendocrinology 8. Pituitary Endocrine Markers 9. Reproductive Endocrinology
Subject Areas: Medical diagnosis [MJA], Medical genetics [MFN], Medical laboratory testing & techniques [MBGL]
