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Effects of Persistent and Bioactive Organic Pollutants on Human Health
David O. Carpenter (Author)
9781118159262, Wiley
Hardback, published 8 October 2013
608 pages
24.4 x 16.3 x 3.6 cm, 0.934 kg
Examines what we know about the relationship between organic chemicals and human disease Organic chemicals are everywhere: in the air we breathe, the water we drink, and the food we eat. They are also found in a myriad of common household and personal care products. Unfortunately, exposure to some organic chemicals can result in adverse health effects, from growth and developmental disorders to cancer and neurodegenerative diseases. This book examines how organic chemicals affect human health. It looks at the different diseases as well as how individual organ systems are affected by organic chemicals. Effects of Persistent and Bioactive Organic Pollutants on Human Health begins with an introductory chapter explaining why we should care about organic chemicals and their effect on human health. Next, the authors address such important topics as: The book ends with an assessment of how much human disease is caused by organic chemicals. Chapters have been contributed by leading international experts in public and environmental health and are based on the latest research findings. Readers will find that all of the contributions are clear and easy to comprehend, with extensive references for further investigation of individual topics. Effects of Persistent and Bioactive Organic Pollutants on Human Health is recommended for students and professionals in medicine as well as public and environmental health, bringing them fully up to date with what we know about the relationship between organic chemicals and human health.
Contributors vii 1. Introduction: Why Should We Care about Organic Chemicals and Human Health? 1 2. Sources of Human Exposure 8 3. The Burden of Cancer from Organic Chemicals 26 4. Carcinogenicity and Mechanisms of Persistent Organic Pollutants 57 5. Diabetes and the Metabolic Syndrome 101 6. Mechanistic Basis for Elevation in Risk of Diabetes Caused by Persistent Organic Pollutants 130 7. Cardiovascular Disease and Hypertension 143 8. Obesity 174 9. Effects and Predicted Consequences of Persistent and Bioactive Organic Pollutants on Thyroid Function 203 10. An Overview of the Effects of Organic Compounds on Women’s Reproductive Health and Birth Outcomes 237 11. Effects of Organic Chemicals on the Male Reproductive System 315 12. Effects of Endocrine-Disrupting Substances on Bone and Joint 332 13. Organic Chemicals and the Immune System 362 14. Exposures to Organic Pollutants and Respiratory Illnesses in Adults and Children 384 15. Cognitive Function 400 16. Intellectual Developmental Disability Syndromes and Organic Chemicals 421 17. Mechanisms of the Neurotoxic Actions of Organic Chemicals 448 18. Parkinson’s Disease 471 19. Psychiatric Effects of Organic Chemical Exposure 514 20. Growth and Development 532 21. How Much Human Disease Is Caused by Exposure to Organic Chemicals? 557 Index 570
David O. Carpenter
Martí Nadal and José L. Domingo
Molly M. Jacobs, Rachel I. Massey, and Richard W. Clapp
Gabriele Ludewig, Larry W. Robertson, and Howard P. Glauert
Duk-Hee Lee and David R. Jacobs, Jr.
Jérôme Ruzzin
Marian Pavuk and Nina Dutton
Eveline Dirinck, Adrian Covaci, Luc Van Gaal, and Stijn Verhulst
Stefanie Giera and R. Thomas Zoeller
Susan R. Reutman and Juliana W. Meadows
Lars Rylander and Anna Rignell-Hydbom
Chi-Hsien Chen and Yueliang Leon Guo
David O. Carpenter
Krassi Rumchev, Jeff Spickett, and Janelle Graham
Lizbeth López-Carrillo and Mariano E. Cebrián
David O. Carpenter
David O. Carpenter
Samuel M. Goldman
James S. Brown, Jr.
Lawrence M. Schell, Mia V. Gallo, and Kristopher K. Burnitz
David O. Carpenter
Subject Areas: Chemistry [PN]
