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Effects of Genome Structure and Sequence on the Generation of Variation and Evolution, Volume 1267
Lynn H. Caporale (Edited by), LH Caporale (Author)
9781573318877, Wiley
Paperback / softback, published 26 October 2012
252 pages
25.4 x 18 x 0.5 cm, 0.281 kg
The structure of DNA varies along its sequence, which can lead to sequence-dependent variations in the fidelity of DNA copying and repair. And because the probability of distinct classes of mutations varies along a DNA sequence, variation that affects fitness will have evolutionary implications, as selection acts on heritable variation. This Annals volume brings together a broad interdisciplinary group of researchers to explore the impact of increasing understanding of DNA structure, repair, replication, and organization on interrelated subjects ranging from evolution, to dependence of the effect of mutagens on environmental and sequence context, to noncanonical forms of information representation in genomes. NOTE: Annals volumes are avaialble for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit http://ordering.onlinelibrary.wiley.com/subs.asp?ref=1749-6632&doi=10.111/(ISSN)1749-6632 ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to Annals online and discounts on print volumes. Please visit http://www.nyas.org/MemberCenter/Joun.aspx for more information about becoming a member.
Overview of the creative genome: effects of genome structure and sequence on the generation of variation and evolution 1. Genome hyperevolution and the success of a parasite 11. The tricky path to recombining X and Y chromosomes in meiosis 18. Sites of genetic instability in mitosis and cancer 24. The genome: an isochore ensemble and it’s evolution 31. Multiple levels of meaning in DNA sequences, and one more 35. Evolution of simple sequence repeat-mediated phase variation in bacterial genomes 39. Indirect selection of implicit mutation protocols 45. G4 motifs in human genes 53. Adaptive radiation of venomous marine snail lineages and the accelerated evolution of venom peptide genes 61. Integrons and gene cassettes: hotspots of diversity in bacterial genomes 71. Creative deaminases, self-inflicted damage, and genome evolution 79. Three-dimensional architecture of the IgH locus facilitates class switch recombination 86. Preaching about the converted: how meiotic gene conversion influences genomic diversity 95. Gross chromosomal rearrangement mediated by DNA replication in stressed cells: evidence from Escherichia coli 103. Implications of genetic heterogeneity in cancer 110. Corrigendum for Ann. N.Y. Acad. Sci. 2009. 1182: 47-57 117.
Lynn Helena Caporale
J. David Barry, James P. J. Hall, and Lindsey Plenderleith
Liisa Kauppi, Maria Jasin, and Scott Keeney
Anne M. Casper, Danielle M. Rosen, and Kaveri D. Rajula
Giorgio Bernardi
Edward N. Trifonov, Zeev Volkovich, and Zakharia M. Frenkel
Christopher D. Bayliss and Michael E. Palmer
David G. King
Nancy Maizels
Baldomero M. Olivera, Maren Watkins, Pradip Bandyopadhyay, Julita S. Imperial, Edgar P. Heimer de la Cotera, Manual B. Aguilar, Estuardo Lopez Vera, Gisela P. Concepcion, and Arturo Lluisma
Ruth M. Hall
Silvestro G. Conticello
Amy L. Kenter, Scott Feldman, Robert Wuerffel, Ikbel Achour, Lili Wang, and Satyendra Kumar
Francesca Cole, Scott Keeney, and Maria Jasin
J.M. Moore, Hallie Wimberly, P.C. Thorton, Susan M. Rosenberg, and P.J. Hastings
Michael W. Schmitt, Marc J. Prindle, and Lawrence A. Loeb
Subject Areas: Biology, life sciences [PS]
