Dynamics of Proteins and Nucleic Acids

Covering reviews of methodology and research in all aspects of protein chemistry, including purification/expression, proteomics, modeling and structural determination and design, each volume brings forth new information about protocols and analysis of proteins while presenting the most recent findings from leading experts in a broad range of protein-related topics.

Tatyana Karabencheva-Christova (Volume editor)

9780124116368

Hardback, published 9 October 2013

368 pages
22.9 x 15.1 x 2.5 cm, 0.57 kg

"The authority, originality, and editing of the reviews are first class." -- NATURE

Approx.358 pages

1. Drug-DNA Intercalation: From Discovery to the Molecular Mechanism

Arnab Mukherjee and Wilbee D. Sasikala

2. Ligand Docking Simulations by Generalized-Ensemble Algorithms

Yuko Okamoto, Hironori Kokubo and Toshimasa Tanaka

3. Conformational Dynamics of Single Protein Molecules Studied by Direct Mechanical Manipulation

Pétur O. Heidarsson, Mohsin M. Naqvi, Punam Sonar, Immanuel Valpapuram and Ciro Cecconi

4. Generation of Ligand Specificity and Modes of Oligomerisation in b -Prism I Fold Lectins

Thyageshwar Chandran, Alok Sharma and Mamannamana Vijayan

5. Conformational Changes of Enzymes and DNA in Molecular Dynamics: Influenced by pH, Temperature, and Ligand

Wen-Ting Chu and Qing-Chuan Zheng

6. Protein Functional Dynamics in Multiple Time Scales as Studied by NMR Spectroscopy

Gabriel Ortega, Miquel Pons and Oscar Millet

7. Protein-DNA Electrostatics: Toward a New Paradigm for Protein Sliding

Maria Barbi and Fabien Paillusson

8. Structural and Dynamical Aspects of HIV-1 Protease and its Role in Drug Resistance Seema Patel and Biswa Ranjan Meher

Subject Areas: Molecular biology [PSD], Proteins [PSBC], Biochemistry [PSB], Organic chemistry [PNN]