Drug Discovery Targeting Drug-Resistant Bacteria

Discusses the status of drug discovery and possible future developments in fighting drug-resistant bacteria

Prashant Kesharwani (Edited by), Sidharth Chopra (Edited by), Arunava Dasgupta (Edited by)

9780128184806

Paperback, published 15 May 2020

432 pages, 65 illustrations
23.4 x 19 x 2.7 cm, 0.88 kg

"This book provides quality information and is a good educational tool." --Doody

Drug Discovery Targeting Drug-Resistant Bacteria explores the status and possible future of developments in fighting drug-resistant bacteria. The book covers the majority of microbial diseases and the drugs targeting them. In addition, it discusses the potential targeting strategies and innovative approaches to address drug resistance. It brings together academic and industrial experts working on discovering and developing drugs targeting drug-resistant (DR) bacterial pathogens. New drugs active against drug-resistant pathogens are discussed, along with new strategies being used to discover molecules acting via new modes of action. In addition, alternative therapies such as peptides and phages are included.

1. What are drugs and why are they required?2. Drugs against gram-negative bacteria3. Drugs targeting gram-positive bacteria4. Drug repurposing against bacteria5. Drugs against M. tuberculosis6. Drugs against TB and Bioweapons7. New approaches to drug discovery: Peptides/quorum sensing/virulence8. New strategies and targets for antibacterial discovery9. Targeting efflux pumps for AMR10. Discovering antibiotics from Phages11. Drugs against non-tuberculous mycobacteria

Subject Areas: Organic chemistry [PNN], Pharmacology [MMG], Clinical trials [MBGR1], Pharmaceutical industries [KNDP]