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Diseases of the Nervous System
Tutorial introduction to science and clinical presentation of core diseases of the nervous system - 2016 PROSE Award winner of Best Textbook Award in Biological & Life Sciences
Harald Sontheimer (Author)
9780128002445, Elsevier Science
Hardback, published 13 March 2015
520 pages
23.4 x 19 x 3.1 cm, 1.04 kg
"...a unique volume that outlines the principal clinical features of all the major neurological and psychiatric diseases while simultaneously discussing the current understanding of the basic science of these disorders...I also would recommend the publication as one that will offer useful insights on disease to all graduate students in neuroscience and it is likely to be helpful to clinicians being trained in neurology and psychiatry." --The Quarterly Review of Biology
The study of the brain continues to expand at a rapid pace providing fascinating insights into the basic mechanisms underlying nervous system illnesses. New tools, ranging from genome sequencing to non-invasive imaging, and research fueled by public and private investment in biomedical research has been transformative in our understanding of nervous system diseases and has led to an explosion of published primary research articles. Diseases of the Nervous System summarizes the current state of basic and clinical knowledge for the most common neurological and neuropsychiatric conditions. In a systematic progression, each chapter covers either a single disease or a group of related disorders ranging from static insults to primary and secondary progressive neurodegenerative diseases, neurodevelopmental illnesses, illnesses resulting from nervous system infection and neuropsychiatric conditions. Chapters follow a common format and are stand-alone units, each covering disease history, clinical presentation, disease mechanisms and treatment protocols. Dr. Sontheimer also includes two chapters which discuss common concepts shared among the disorders and how new findings are being translated from the bench to the bedside. In a final chapter, he explains the most commonly used neuroscience jargon. The chapters address controversial issues in current day neuroscience research including translational research, drug discovery, ethical issues, and the promises of personalized medicine. This book provides an introduction for course adoption and an introductory tutorial for students, scholars, researchers and medical professionals interested in learning the state of the art concerning our understanding and treatment of diseases of the nervous system.
Introduction Section I. Static Nervous System Diseases1. Cerebrovascular Infarct - Stroke2. Central Nervous System Trauma3. Seizure Disorders and Epilepsy Section II. Progressive Neurodegenerative Diseases4. Aging, Dementia, and Alzheimer’s Disease5. Parkinson’s Disease6. Diseases of Motor Neurons and Neuromuscular Junctions7. Huntington’s Disease Section III. Secondary Progressive Neurodegenerative Diseases8. Multiple Sclerosis9. Brain Tumors10. Infectious Diseases of the Nervous System Section IV. Developmental Neurological Conditions11. Neurodevelopmental Disorders Section V. Neuropsychiatric Illnesses12. Mood Disorders and Depression13. Schizophrenia Section VI. Common Concepts in Neurological and Neuropsychiatric Illnesses14. Shared Mechanisms of Disease Section VII. Bench-to-Bedside Translation15. Drug Discovery and Personalized Medicine Section VIII. Neuroscience Jargon16. "Neuro"-dictionary
Subject Areas: Neurosciences [PSAN], Neurology & clinical neurophysiology [MJN], Physiology [MFG]