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Disease-Modifying Targets in Neurodegenerative Disorders
Paving the Way for Disease-Modifying Therapies
Comprehensive reference on different neurodegenerative disorders, their molecular pathology, and present and future disease-modifying therapies
Veerle Baekelandt (Edited by), Evy Lobbestael (Edited by)
9780128051207, Elsevier Science
Hardback, published 1 April 2017
320 pages
23.4 x 19 x 2.4 cm, 0.75 kg
Disease-Modifying Targets in Neurodegenerative Disorders: Paving the Way for Disease-Modifying Therapies examines specific neurodegenerative disorders in comprehensive chapters written by experts in the respective fields. Each chapter contains a summary of the disease management field, subsequently elaborating on the molecular mechanisms and promising new targets for disease-modifying therapies. This overview is ideal for neuroscientists, biomedical researchers, medical doctors, and caregivers, not only providing readers with a summary of the way patients are treated today, but also offering a glance at the future of neurodegenerative disorder treatment.
1. The multitude of therapeutic targets in neurodegenerative proteinopathies 2. Synuclein misfolding as a therapeutic target 3. Neuroinflammation as a therapeutic target in neurodegenerative diseases 4A. Stem cells in neurodegeneration: mind the gap 4B. The potential of stem cells in tackling neurodegenerative diseases 5. Preclinical models of Alzheimer’s disease for identification and preclinical validation of therapeutic targets: from fine-tuning strategies for validated targets to new venues for therapy 6. Parkinson’s disease 7. Lewy body dementia 8. Frontotemporal dementia 9. From huntingtin gene to Huntington’s disease-altering strategies 10. Amyotrophic lateral sclerosis: mechanisms and therapeutic strategies
Subject Areas: Neurology & clinical neurophysiology [MJN]
