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Discovery and Development of Neuroprotective Agents from Natural Products
Reviews medicinal chemistry and latest progress in the identification and chemical development of neuroprotective agents from natural sources
Goutam Brahmachari (Edited by)
9780128095935
Paperback / softback, published 13 June 2017
490 pages
22.9 x 15.1 x 3.1 cm, 0.77 kg
"The book should appeal to a broad audience with diverse backgrounds including chemistry, biology, pharmacy, and medicine. It can also be a valuable resource for researchers, academicians, and graduate students. In addition to enjoying the book’s content, its readers will probably be able to identify viable research directions for the discovery and development of new and promising neuroprotective agents." --Ehab A. Abourashed, Journal of Natural Products Chemistry, Aug 2018
Discovery and Development of Neuroprotective Agents from Natural Products draws together global research on medicinal agents from natural sources as starting points for the design of neuroprotective drugs. From the prediction of promising leads and identification of active agents to the extraction of complex molecules, the book explores a range of important topics to support the development of safer, more economical therapeutics for these increasingly prevalent diseases. Beginning with an overview of current developments in the field, the book goes on to explore the identification, extraction and phytochemistry of such neuroprotective agents as antioxidants, biophenols and naturally occurring anti-inflammatory steroid analogues. Specific natural sources of bioactive agents are reviewed, and the development of these agents into therapeutics for a number of specific neurological disorders, including Alzheimer’s disease, Parkinson’s disease and ischemic brain stroke, are discussed. Combining the expertise of specialists from around the world, this in the Natural Products Drug Discovery series aims to support and encourage researchers in the investigation of natural sources as starting points for the development of standardized, safe and effective neuroprotective drugs.
1. Natural Products as a source of neuroprotective agents for Parkinson’s Disease 2. Discovery of neuroprotective antioxidants for the management of ischemic brain stroke 3. Discovery of biophenols for application in Alzheimer’s Disease 4. Identification and Development of Naturally Occurring Anti-Inflammatory Steroid Analogues for Neuroprotection 5. Neuroprotective plant alkaloids: structure activity and synthetic analogues 6. Coumarin-based molecules as suitable models for developing new neuroprotective agents through structural modification 7. Phytochemistry and Pharmacology of Lycium barbarum L. and Schisandra chinensis (Turcz.) Baill" or "Neuroprotective phytochemicals of Lycium barbarum L. and Schisandra chinensis (Turcz.) Baill" 8. Neuroactive Components of Culinary and Medicinal Mushrooms with Potential to Mitigate Age Related Neurodegenerative Diseases
