Development of T Cell Immunity
Provides new insights into the etiology of human autoimmune disease
Adrian Liston (Volume editor)
9780123812841, Elsevier Science
Hardback, published 28 October 2010
342 pages
22.9 x 15.1 x 2.4 cm, 0.61 kg
PRAISE FOR THE SERIES:
"Full of interest not only for the molecular biologist--for whom the numerous references will be invaluable--but will also appeal to a much wider circle of biologists, and in fact to all those who are concerned with the living cell." --British Medical Journal
T cells belong to a group of white blood cells called lymphocytes and play a large role in the immune response. An increased understanding of T cell immunity will provide new insights into the etiology of human autoimmune disease such as diabetes.
This volume reviews the latest developments and discusses the evolution of T cell immunity, thymic requirements, and how to prevent T cell-dependent autoimmunity.
Development of T cell immunity
- The development of T cell immunity – Adrian Liston
The evolution of T cell immunity
- Genome duplication and T cell immunity – Masanori Kasahara
- Questions arising from "Genome duplication and T cell immunity" – Claude Perreault
- Response to questions – Masanori Kasahara
- The origin and role of MHC class I-associated self peptides – Claude Perreault
- Questions arising from "The origin and role of MHC class I-associated self peptides" – Masanori Kasahara
- Response to questions – Claude Perreault
Thymic requirements for T cell immunity
- Transcriptional regulation of thymus organogensis and thymic epithelial cell differentiation – Nancy Manley and Brian Condie
- Early T cell differentiation: lessons from T-cell acute lymphoblastic leukemia – Cedric S Tremblay, Thu Hoang and Trang Hoang
T cell immunity in the periphery
- Lymphoid tissue inducer cells and the evolution of CD4 dependent high affinity antibody responses – Peter J L Lane, Fiona M McConnell, David Withers, Fabrina Gaspal, Manoj Saini and Graham Anderson
- Commentary on "Lymphoid tissue inducer cells and the evolution of CD4 dependent high affinity antibody responses" – Mark Coles, Dimitri Kioussis and Henrique Veiga-Fernandes
- Cellular and Molecular Requirements in Lymph Node and Peyer’s Patch Development – Mark Coles, Dimitri Kioussis and Henrique Veiga-Fernandes
- T follicular helper cells during Immunity and Tolerance – Michelle A. Linterman and Carola G. Vinuesa
Preventing T cell-dependent autoimmunity
- Thymic selection and lineage commitment of CD4+Foxp3+ regulatory T cells – Paola Romagnoli and Joost P.M. van Meerwijk
- Molecular Mechanisms of Regulatory T cell Development and Suppressive Function – Jeong M. Kim
- Is Foxp3 the master regulator of regulatory T cells? – Adrian Liston
Subject Areas: Cellular biology [cytology PSF], Immunology [MJCM]
