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Detection of Drugs and Their Metabolites in Oral Fluid
An up-to-date guide on the methods involved in oral fluid analysis for pharmaceutical detection
Robert M. White (Author), Christine M. Moore (Author)
9780128145951
Paperback, published 27 February 2018
140 pages
22.9 x 15.1 x 1 cm, 0.23 kg
Detection of Drugs and Their Metabolites in Oral Fluid presents the analytical chemistry methods used for the detection and quantification of drugs and their metabolites in human oral fluid. The authors summarize the state of the science, including its strengths, weaknesses, unmet methodological needs, and cutting-edge trends. This volume covers the salient aspects of oral fluid drug testing, including specimen collection and handling, initial testing, point of collection testing (POCT), specimen validity testing (SVT), and confirmatory and proficiency testing. Analytes discussed include amphetamines, cannabinoids, cocaine, opiates, phencyclidine, cannabimimetics, and miscellaneous drugs. This practical guide helps users turn knowledge into practice, moving logically from an outline of the problem, to the evaluation of the appropriateness of oral fluid as a test medium, and finally to a consideration of detection methods and their validation and employment.
1. Introduction2. Oral Fluid Pharmacokinetics3. Collection of Oral Fluid4. Point of Collection Testing5. Initial Testing 6. Specimen Validity Testing (SVT) 7. Confirmatory Testing 8. Proficiency Testing9. Individual Analytes, Specimen Handling, Stability, and Other Issues10. Concluding Remarks
Subject Areas: Analytical chemistry [PNF], Forensic medicine [MMQ], Medical toxicology [MMGT], Pharmacology [MMG], Criminal investigation & detection [JKVF]
