Detection Methods for Cynobacterial toxins

G A Codd (Edited by), T M Jefferies (Edited by), C W Keevil (Edited by), E Potter (Edited by)

9781855738027, Elsevier Science

Hardback, published 1 January 1994

202 pages
24.1 x 15.9 x 2 cm, 0.44 kg

Cyanobacteria, or blue-green algae, commonly occur in a variety of water types throughout the world. A variable, but, high proportion of the cyanobacterial blooms and scums, which can develop annually in lakes, reservoirs, canals and slow-flowing rivers, contain potent toxins. Although animal poisonings and human health problems associated with the ingestion of, or contact with, cyanobacterial scums have long been recognized, a developing understanding of the health hazards posed by the toxins requires that reliable, sensitive, specific and convenient methods are available for their detection and quantification.

Detection methods for cynobacterial toxins looks at the application of biological, toxicological, biochemical and physicochemical techniques in studies of cyanobacterial toxins and at experimental methods that have identified at least 50 cyanobacterial compounds toxic to vertebrates.

Academics, public health bodies, environmental protection agencies and water companies are all involved in monitoring cyanobacterial levels and effects, and this book will help to ensure that their research is not duplicated, is standardized and comparable, and that optimal progress can be made in an important area that is still in its developing stages.

Health problems from exposure to cyanobacteria and proposed safety guidelines for drinking and recreational water
An epidemiological critique of reports of human illness associated with cyanohacteria
Cyclic peptide hepatotoxins from fresh water cyanobacteria water blooms collected in the river dnieper reservoirs and other water bodies from the European part of Russia
Structural analysis of cyanobacterial toxins
Determinations of anatoxin-a, homoanatoxin and propylanatoxin in cyanobacterial extracts by HPLC, GC-mass spectrometry and capillary electrophoresis
Enantiomer-specific analysis of homoanatoxin-a. a cyanophyte neurotoxin
Neurotoxins from Australian Anabaena
The analysis of microcystin-LR in water: Application in water treatment studies
The analysis of microcystins in raw and treated water
Application of HPLC and mass spectrometry (MALDI) to the detection and identification of toxins from microcystis, oscillatoria and aphanizomenon from several freshwater reservoirs
Routes of intoxication
Testing of toxicity in cyanobacteria by cellular assays
A sensitive bioscreen for detection of cyclic peptide toxins of the microcystin class
The inhibition of protein phosphatases by toxins: Implications for health and an extremely sensitive and rapid bioassay for toxin detection
Detection of hepatotoxins by protein phosphatase inhibition assay: advantages, pitfalls and anomalies
Alternatives to the mouse bioassay for cyanobacterial toxicity assessment
Evaluation of assay methods for the determination of cyanobacterial hepatotoxicity
The role of synthetic chemistry in the production of standards for toxin analysis
Sources of uncertainty in assessing the health risk of cyanobacterial blooms in drinking water supplies
Standing committee of analysts
Toxic cyanobacteria (blue-green algae) in Portuguese freshwaters
Screening of cyanobactenal toxins in microcystis aeruginosa collected from blooms and cultures
Toxicity studies with blue-green algae from Flemish reservoirs
Cases of cyanobacterial toxicoses on Swiss alpine pastures
Biological and economic significance of benthic cyanobacteria in two Scottish highland lochs
First results on the occurrence of microcystin-LR in Berlin and Brandenburg lakes
Variation of cyanobacterial hepatotoxins in Finland
A method for the detection of cyanobacterial peptide toxins by HPLC
Release and degradation of microcystin during a microcystis aeru bloom in a freshwater reservoir
Characterization of hepatotoxins from freshwater oscillatoria species: Variation in toxicity and temporal expression
Expression of cyanotoxins in environmental biomass containing species of oscillatoria
A simple and rapid method for extraction of toxic peptides from cyanobacteria
Phosphatase assay as a determinant of hepatotoxin toxicity
Detection of cyanobacterial (blue-green algal) peptide toxins by protein phosphatase inhibition
Investigation of the solution conformation of microcystins-LR and -RR by high field nuclear magnetic resonance
The tandem mass spectrometry of nodularin, microcystins and other cyclic peptides.

Subject Areas: Food & beverage technology [TDCT]