Design and Analysis of Clinical Experiments

Joseph L. Fleiss (Author)

9780471349914, Wiley

Paperback / softback, published 25 March 1999

448 pages
23 x 15.4 x 2 cm, 0.601 kg

First published in 1986, this unique reference to clinical experimentation remains just as relevant today. Focusing on the principles of design and analysis of studies on human subjects, this book utilizes and integrates both modern and classical designs. Coverage is limited to experimental comparisons of treatments, or in other words, clinical studies in which treatments are assigned to subjects at random.

Reliability of Measurement.

Simple Linear Regression Analysis.

The Parallel Groups Design.

Special Cases of the Parallel Groups Study.

Blocking to Control for Prognostic Variables.

Stratification to Control for Prognostic Variables.

Analysis of Covariance and the Study of Change.

Repeated Measurements Studies.

Latin and Greco-Latin Squares.

The Crossover Study.

Balanced Incomplete Block Designs.

Factorial Experiments.

Split-Plot Designs and Confounding.

Appendix.

Indexes.

Subject Areas: Mathematics [PB]