CRISPR in Animals and Animal Models

Contains cutting-edge reviews of molecular biology, with this edition focusing on CRISPR in animals and animal models

Raul Torres-Ruiz (Volume editor), Sandra Rodriguez-Perales (Volume editor)

9780128125069, Elsevier Science

Hardback, published 10 November 2017

148 pages
22.9 x 15.1 x 1.8 cm, 0.45 kg

Praise for the Series:
"Maintains the tradition and set-up of the previous volumes and certainly provides up-to-date data on varied aspects of cytology... a valuable acquisition to any library." --The Nucleus

CRISPR in Animals and Animal Models, Volume 152, the latest release in the Progress in Molecular Biology and Translational Science series, explores the genome editing CRISPR system in cells and animal models, its applications, the uses of the CRISPR system, and the past, present and future of CRISPR genome editing. Topics of interest in this updated volume include a section on CRISPR history, The genome editing revolution, Programming CRISPR and its applications, CRISPR Delivery methods, CRISPR libraries and screening, CRISPR investigation in haploid cells, CRISPR in the generation of transgenic animals, CRISPR therapeutics, and Promising strategies and present challenges.

1. CRISPR History: Discovery, Characterization, and Prosperity Wenyuan Han and Qunxin She 2. CRISPR/Cas9 Technology: Applications and Human Disease Modeling Marta Martinez-Lage, Raúl Torres-Ruiz and Sandra Rodriguez-Perales 3. Dynamics of Indel Profiles Induced by Various CRISPR/Cas9 Delivery Methods Michael Kosicki, Sandeep Sundara Rajan, Flaminia C. Lorenzetti, Hans H. Wandall, Yoshiki Narimatsu, Emmanouil Metzakopian and Eric P. Bennett 4. CRISPR Libraries and Screening John T. Poirier 5. Genome Engineering Using Haploid Embryonic Stem Cells Takuro Horii and Izuho Hatada 6. CRISPR in Animals and Animal Models Ellen Shrock and Marc Guell 7. Gene Editing and CRISPR Therapeutics: Strategies Taught by Cell and Gene Therapy Juan C. Ramirez

Subject Areas: Molecular biology [PSD], Biochemistry [PSB]