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Contemporary Chemical Approaches for Green and Sustainable Drugs

Holistic guide to key problems, approaches and tools that support environmentally-conscious drug design and discovery

Marianna Torok (Edited by)

9780128222485, Elsevier Science

Paperback, published 26 August 2022

566 pages, 400 illustrations (50 in full color)
22.9 x 15.1 x 3.5 cm, 1.25 kg

Contemporary Chemical Approaches for Green and Sustainable Drugs provides readers with the knowledge they need to integrate sustainable approaches into their work. Sections cover different aspects of green and sustainable drug development from design to disposal, including computer-aided drug design, green resourcing of drugs and drug candidates, an overview of the health concerns of pharmaceutical pollution, and a survey of potential chemical methods for its reduction. Drawing together the knowledge of a global team of experts, this book provides an inclusive overview of the chemical tools and approaches available for minimizing the negative environmental impact of current and newly developed drugs.

This will be a useful guide for all academic and industrial researchers across green and sustainable chemistry, medicinal chemistry, environmental chemistry and pharmaceutical science.

1. Using the Zebrafish Model System to Identify the Health Effects of Pharmaceutical Pollutants 2. Analysis of Pharmaceuticals in the Environment 3. Leaking of Antibiotics in the Aquatic Environment 4. Advances in Drug Development with the Application of Artificial Intelligence 5. Virtual Screening Techniques in Pharmaceutical Research 6. In Silico Modeling of Environmental Toxicity of Drugs 7. Sustainable Separations in Pharmaceutical Manufacturing 8. Green Synthetic Methods in Drug Discovery and Development 9. Green Metrics of Drug Synthesis 10. Green chemistry approaches to drugs that treat epidemic and pandemic diseases 11. Dynamic Effects of Organic Molecules for Drug Delivery in Micelles 12. Antibody-Drug Conjugates for Targeted Delivery 13. Green Peptide-based Drugs 14. The Multitarget Approach as a Green Tool in Medicinal Chemistry 15. Directed Evolution: A New Powerful Tool in Drug Development 16. Conventional and Advanced Treatment Methods for the Removal of Pharmaceuticals and Related Compounds in Wastewater

Subject Areas: Organic chemistry [PNN], Chemistry [PN], Pharmacology [MMG]

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