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Colloid and Interface Science in Pharmaceutical Research and Development
The first comprehensive book on pharmaceutical research based on colloid and interface science
Hiroyuki Ohshima (Edited by), Kimiko Makino (Edited by)
9780444626141, Elsevier Science
Hardback, published 18 July 2014
532 pages, 20 illustrations
23.4 x 19 x 3.1 cm, 1.12 kg
Colloid and Interface Science in Pharmaceutical Research and Development describes the role of colloid and surface chemistry in the pharmaceutical sciences. It gives a detailed account of colloid theory, and explains physicochemical properties of the colloidal-pharmaceutical systems, and the methods for their measurement. The book starts with fundamentals in Part I, covering fundamental aspects of colloid and interface sciences as applied to pharmaceutical sciences and thus should be suitable for teaching. Parts II and III treat applications and measurements, and they explains the application of these properties and their influence and use for the development of new drugs.
Part I Fundamentals Interaction between drugs Pharmaceutical suspensions Response of colloidal drugs to external fields Aggregation of drugs Concentrated drug particles Rheology of colloidal suspensions Part II Applications of Colloid and Interface Science in Pharmaceutical sciences Liposomes and micelles Binding of drugs on liposomes Drug delivery system Gold nanoparticles Drug permeation through biological membranes EPR effects Part III Measurements Zeta potential of colloidal drugs Atomic force microscope Surface force apparatus
Subject Areas: Pharmaceutical technology [TDCW], Chemical engineering [TDCB], Surface chemistry & adsorption [PNRX], Pharmacology [MMG]