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Chinmedomics
The Integration of Serum Pharmacochemistry and Metabolomics to Elucidate the Scientific Value of Traditional Chinese Medicine

A comprehensive treatment of Chinmedomics, a unique research method for evaluating the biological characteristics of Traditional Chinese Medicine (TCM) syndromes and the efficacy of TCM formulae to provide safer, more effective drug development and therapy

Xijun Wang (Author), Aihua Zhang (Author), Hui Sun (Author)

9780128031179

Hardback, published 29 September 2015

408 pages, 100 illustrations (100 in full color)
23.4 x 19 x 2.7 cm, 0.97 kg

Chinmedomics: The Integration of Serum Pharmacochemistry and Metabolomics to Elucidate the Scientific Value of Traditional Chinese Medicine uses new experimental techniques and research to open doors in drug discovery and development related to traditional Chinese medicine (TCM). This book features a unique approach that combines chemometric analysis with metabolomics studies to illuminate significant changes that have occurred in syndrome states while simultaneously analyzing the efficacy of chemical ingredients in herbal medicines. Chapters provide cutting-edge information on traditional medicine, analytical technology, natural products, metabolomics, bioinformatics and their applications. This book provides a valuable resource for pharmacologists, pharmaceutical scientists, medicinal plant researchers, pharmacognosists and chemists working with TCM and highlights ways to further research and advances in this area in the future.

Preface

  1. Origin of Chinmedomics
  2. Methods and protocols of Chinmedomics
  3. Chinmedomics advancing drug discovery and development from Yinchenhao Tang
  4. Chinmedomics approach dissects therapeutic properties of ShenQiWan acting on ShenYangXu syndrome
  5. Metabolic profiling and biomarkers analysis of Jaundice syndrome
  6. Metabolic profiling and biomarkers analysis of GanYuPiXU syndrome
  7. Metabolic profiling and biomarkers of Yinhuang syndrome and evaluation on Yinchensini Tang
  8. Metabolite profiling and biomarkers analysis of Jaundice syndrome related animal model
  9. Metabolomic evaluation of hepatoprotective effect of Yinchenhao Tang and its major bioactive constituents
  10. Metabolomics and proteomics elucidation on therapeutic mechanisms of geniposide
  11. Metabolic profiling and potential biomarkers of ShenYinXu syndrome and therapeutic effect of Liuweidihuang Wan
  12. Metabolic profiling of healthy persons treated with Liuweidihuang Wan
  13. Metabolic profiling and potential biomarkers analysis of ShenYangXu syndrome
  14. Metabolic evaluation of ShenQiWan nourishing ShenYangXu syndrome
  15. Metabolic profiling and biomarkers analysis of XinQiXu syndrome
  16. Active constituents screening based on correlation analysis between marker metabolites and absorbed constituents in Wen-Xin-Formula
  17. Targeted synergism effects of the combined active constituents of Yinchenhao Tang
  18. Metabolic profiling and biomarkers of type 2 diabetes and effective evaluation of Tianqi Jiangtang capsule
  19. Metabolic biomarkers of alcohol liver damage and intervention effect of Yinchenhao Tang
  20. Metabolic profiling and biomarkers analysis of insomnia and intervention effects of Suanzaoren decoction and its related active ingredients
  21. Metabolic biomarkers of nonbacterial prostatitis and treatment evaluation of Phellodendri amurensis cortex and its main components
  22. Metabolic profiling provides a system for understanding of Alzheimer's disease in rats after treatment with Kaixin San
  23. Metabolic profiles delineate the effect of Shengmai San on Alzheimer's disease in rats

Subject Areas: Molecular biology [PSD], Organic chemistry [PNN], Pharmacology [MMG]

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