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Cell Death Regulation in Health and Disease - Part A

The current state of knowledge in the field of regulated cell death, covering multiple different pathways, organisms and disease settings

Lorenzo Galluzzi (Volume editor), Johan K.E. Spetz (Volume editor)

9780128201336, Elsevier Science

Hardback, published 25 March 2020

252 pages
22.9 x 15.1 x 2.1 cm, 0.52 kg

Cell Death Regulation in Health and Disease - Part A, Volume 351, the latest release in the International Review of Cell and Molecular Biology reviews current advances in cell and molecular biology. The series publishes timely topics authored by prominent cell and molecular biologists. This release is part of a 3-part series which comprises a comprehensive view of cell death regulation in a variety of biological contexts. Chapters cover Membrane dynamics in cell death regulation, The role of necroptosis in intestinal dysfunction, Regulation of cell death in the cardiovascular system, Cell death in bacterial and viral infection, and much more.

Preface: Life through death: Key role of cellular suicide for colonial and organismal homeostasis Johan Spetz and Lorenzo Galluzzi

1. Bcl-2 family proteins, beyond the veil Jason Andrew Glab, Zhipeng Cao and Hamsa Puthalakath

2. Mcl-1 as a “barrier? in cancer treatment: Can we target it now? Nikolai V. Pervushin, Viacheslav V. Senichkin, Boris Zhivotovsky and Gelina S. Kopeina

3. TRAIL receptor signaling: From the basics of canonical signal transduction toward its entanglement with ER stress and the unfolded protein response Daniela Stöhr, Albert Jeltsch and Markus Rehm

4. Type 3 IP3 receptors: The chameleon in cancer Nicolas Rosa, Flore Sneyers, Jan B. Parys and Geert Bultynck

5. On the role of sphingolipids in cell survival and death Elisabetta Iessi, Matteo Marconi, Valeria Manganelli, Maurizio Sorice, Walter Malorni, Tina Garofalo and Paola Matarrese

6. A lipid perspective on regulated cell death Hector Flores-Romero, Uris Ros and Ana J. García Sáez

Subject Areas: Cellular biology [cytology PSF], Molecular biology [PSD], Developmental biology [PSC]

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