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Carcinogen-Driven Mouse Models of Oncogenesis

Presents the latest models of mouse models of oncogenesis

Lorenzo Galluzzi (Volume editor), Aitziber Buque (Volume editor)

9780128225349, Elsevier Science

Hardback, published 26 March 2021

256 pages
23.4 x 19 x 2.1 cm, 0.79 kg

Carcinogen-Driven Mouse Models of Oncogenesis, Volume 163 contains a series of protocols written by world-leading experts in the field. Each manuscript provides a detailed methodological description to drive carcinogen-mediated oncogenesis in mice. Chapters in this new release include Chemical carcinogenesis in mice as a model of human cancer: Pros and cons, MPA/DMBA-driven mammary carcinomas, Dimethylbenz(a)anthracene-Induced Mammary Tumorigenesis in mice, Urethane-induced lung carcinogenesis, Methylcholanthrene-induced fibrosarcomas, BBN-driven bladder carcinomas, Oral squamous cell carcinomas driven by 4NQO, Analyzing skin tumor development in mice by the DMBA/TPA model, and much more.

Other sections cover DSS/AOM-driven colorectal carcinomas, Diethylnitrosamine-induced liver tumorigenesis in mice, Two-stage 3-methylcholanthrene and butylated hydroxytoluene-induced lung carcinogenesis in mice, Lung carcinomas induced by NNK and LPS, Pristane-induced mammary carcinomas, The 4-NQO mouse model: an update on a well-established in vivo model of oral carcinogenesis, and more.

1. Preface - Chemical carcinogenesis in mice as a model of human cancer: Pros and cons Lorenzo Galluzzi 2. MPA/DMBA-driven mammary carcinomas Aitziber Buqué Martinez 3. Dimethylbenz(a)anthracene-Induced Mammary Tumorigenesis in mice Isabelle Plante 4. Urethane-induced lung carcinogenesis Silvano Sozzani 5. Methylcholanthrene-induced fibrosarcomas Awen Gallimore 6. BBN-driven bladder carcinomas Janos Terzic 7. Oral squamous cell carcinomas driven by 4NQO Nancy J. Philp 8. Analysing skin tumor development in mice by the DMBA/TPA model Cord Brakebusch 9. DSS/AOM-driven colorectal carcinomas David C. Montrose 10. Diethylnitrosamine-induced liver tumorigenesis in mice Peter Hasselblatt 11. Two-stage 3-methylcholanthrene and butylated hydroxytoluene-induced lung carcinogenesis in mice Alison K. Bauer 12. Lung carcinomas induced by NNK and LPS Peter Di 13. Pristane-induced mammary carcinomas Bae Hoon Lee 14. The 4-NQO mouse model: an update on a well-established in vivo model of oral carcinogenesis Pierre Saintigny

Subject Areas: Cellular biology [cytology PSF], Molecular biology [PSD], Developmental biology [PSC]

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