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Cancer Treatment and the Ovary
Clinical and Laboratory Analysis of Ovarian Toxicity
Describes both the clinical and laboratory approaches to discovering the potentially adverse effects of cancer treatments on the ovary
Richard A Anderson (Edited by), Norah Spears (Edited by)
9780128015919, Elsevier Science
Paperback, published 21 October 2015
166 pages
22.9 x 15.1 x 1.2 cm, 0.27 kg
Cancer Treatment and the Ovary: Clinical and Laboratory Analysis of Ovarian Toxicity provides the reader with a basic understanding on how the ovary is adversely impacted by cancer treatment, an essential foundational knowledge for this rapidly-developing field. The book describes both the clinical and laboratory approaches to discovering the potentially adverse effects of cancer treatment on the ovary, also laying out possible preventative approaches and future directions for the field. Clinicians working in the field of reproductive biology and oncology will find an essential reference that provides the necessary tools to assess the reproductive toxicological effects of cancer treatments.
Section I: Clinical 1. Ovarian Follicle Biology and the Basis for Gonadotoxicity 2. Relevant Cancer Diagnoses, Commonly Used Chemotherapy Agents and Their Biochemical Mechanisms of Action 3. Clinical Assessment of Ovarian Toxicity 4. The Current Understanding of Clinical Data on Ovarian Toxicity from Cancer Treatment Section II: Laboratory Models 5. In Vivo Models of Ovarian Toxicity 6. In Vitro Models of Ovarian Toxicity Section III: Strategies to Protect the Ovary 7. Ovarian Tissue Cryopreservation for Fertility Preservation 8. Current Clinical Approaches to Protecting the Ovary: GnRH Analogues 9. Preclinical Approaches to the Protection of Ovarian Function
Subject Areas: Developmental biology [PSC], Medical toxicology [MMGT], Endocrinology [MJG], Oncology [MJCL], Birth control, contraception, family planning [MBNH4]
