Cancer in Pregnancy
Maternal and Fetal Risks

The first ever detailed review of the commonest cases of cancer in pregnancy, their treatment and outcome.

G. Koren (Edited by), M. Lishner (Edited by), D. Farine (Edited by)

9780521471763, Cambridge University Press

Hardback, published 28 March 1996

236 pages, 20 b/w illus. 10 tables
23.5 x 15.6 x 1.9 cm, 0.466 kg

"There is a detailed index as well as important information on the impact of pregnancy on survival....this volume will have a long useful life." John J. Mulvihill, Journal of the National Cancer Institute

Cancer in pregnancy, although thankfully a relatively uncommon occurrence, presents physicians and their patients with a major dilemma. The urge to use the highest tolerable doses of chemotherapy, high doses of irradiation and surgery has to be weighed carefully against their risks to the unborn baby. This book is the very first to attempt to quantify these risks and provide physicians with a core of knowledge that will be very relevant to making sound clinical decisions in the face of sometimes conflicting interests. The volume evaluates the results of the Motherisk Program, which was set up specifically to address this problem, and reviews maternal and fetal outcomes from a sizeable database of the most common cases of cancer in pregnancy. In reviewing this program and the experience of others in this area, this volume sets out to create a clinically relevant tool for oncologists, obstetrician-gynecologists, perinatologists and neonatologists.

Preface G. Koren, M. Lishner and D. Farine
Introduction
1. Cancer in pregnancy: Identification of unanswered questions on maternal and fetal risks G. Koren, L. Weiner, M. Lishner, D. Zemelickis and J Finnegan
2. The pregnant patient with malignant disease - maternal fetal conflict D. Farine and E. N. Kelly
3. Changes in drug disposition during pregnancy and its clinical implications G. Koren
4. The role of the placenta in biotransformation of carcinogenic compounds L. Derewlany and G. Koren
5. Antepartum fetal monotoring in the oncologic patient Y. Ezra and K. Panter
6. The Toronto Study Group - Methodological Notes
7. Motherisk - The process of counselling in reproductive toxicology G. Koren and A. Pastuszak
Specific Tumors During Pregnancy: 8. Maternal and fetal outcome following breast cancer in pregnancy D. Zemlickis, M. Lishner, P. Degendorfer, T. Panzarella, B. Burke, S. B. Sutcliffe and G. Koren
9. Maternal and fetal outcome following Hodgkin's disease in pregnancy M. Lishner, D. Zemlickis, P. Degendorfer, T. Panzarella, S. B. Sutcliffe and G. Koren
10. Non-Hodgkin's lymphoma and pregnancy D. Zemlickis, M. Lishner, S. B. Sutcliffe and G. Koren
11. Maternal and fetal outcome following invasive cervical cancer in pregnancy M. Lishner, D. Zemlickis, P. Degendorfer, T. Panzarella, S. B. Sutcliffe and G. Koren
12. Pregnancy and ovarian cancer M. Lishner and G. Koren
13. Malignant melanoma and pregnancy M. Ravid and M. Lishner
14. Leukemia during pregnancy M. Lishner
Fetal Effects of Cancer and its Treatment: 15. Prenatal irradiation and cancer Y. Bentur
16. Review of fetal effects of cancer chemotherapeutic agents D. Zemlickis, M. Lishner and G. Koren
17. Fetal outcome folowing in utero exposure to cancer chemotherapy - The Toronto study D. Zemlickis, M. Lishner, P. Degendorfer, T. Panzarella, S. B. Sutcliffe and G. Koren
18. Intrauterine causes of tumors in later life G. Koren
19. Fetal tumors P. McParland
Index.

Subject Areas: Neonatal medicine [MJWN], Materno-fetal medicine [MJTF], Oncology [MJCL]