Cancer Biomarkers: Clinical Aspects and Laboratory Determination

A comprehensive overview of current pathological biomarkers for cancer detection, monitoring and recurrence

Lakshmi V. Ramanathan (Edited by), Martin Fleisher (Edited by), Michael J. Duffy (Edited by)

9780128243022, Elsevier Science

Paperback, published 15 June 2022

474 pages
23.5 x 19 x 3 cm, 0.97 kg

Cancer Biomarkers: Clinical Aspects and Laboratory Determination provides a comprehensive overview of current biomarkers for cancer detection, monitoring and recurrence, focusing on emerging technologies, impacts on the field, and selected biomarkers currently used in clinical practice. The content highlights current laboratory tests used in the management of adult and pediatric cancer patients. In addition, it investigates the role of Circulating Tumor Cells and circulating tumor DNA as biomarkers in cancer management as well as cytokines in monitoring response to CAR T therapies.

1. Overview of tumor markers, traditional and non-traditional (include glycans)
2. Laboratory testing in pediatric cancer patients
3. The adult cancer patient: overview and current laboratory testing
4. Thyroglobulin measurement: its importance in monitoring and recurrence of thyroid cancer
5. PSA, long term prognosis
6. Monoclonal gammopathy detection and current technologies
7. Liquid biopsy potential and challenges
8. CAR T therapies and the management of toxicity
9. Validating circulating tumor cells and cell free DNA as an LDT for use in the clinic
10. Saliva as a matrix for measurement of biomarkers
11. Emerging technologies in the detection and monitoring of cancer
12. Oncometabolites
13. Circulating cancer biomarkers: current status and future prospects

Subject Areas: Life sciences: general issues [PSA]